Dioscorea opposita reverses dexamethasone induced insulin resistance

	Dioscorea opposita reverses dexamethasone induced insulin resistance
	Gao, XP; Li, BG; Jiang, HW; Liu, FL; Xu, DY; Liu, ZR; Gao, XP, Di Ao Pharmaceut Grp, Inst Mat Med, Chengdu 610041, Peoples R China.
刊名	FITOTERAPIA
	2007
卷号	78 期号:1 页码:12_15
关键词	Dioscorea Opposita Insulin Resistance Dexamethasone 3t3-l1 Adipocytes Glut4
ISSN号	0367-326X
产权排序	2
英文摘要	The effects of Dioscorea opposita (huai shan yao, HSY) on dexamethasone-induced insulin resistance were investigated in vitro and in vivo. D. opposita extract reduced significantly the blood insulin and glucose levels in dexamethasone-induced diabetic rats. In vitro, HSY significantly enhanced insulin-stimulated glucose uptake in 3T3-L1 adipocytes. Moreover, HSY increase the mRNA expression of GLUT4 glucose transporter in 3T3-L1 adipocytes. These data suggest that D. opposita has insulin sensitivity that is associated with the regulation of GLUT4 expression. (c) 2006 Elsevier B.V. All rights reserved.
学科主题	Chemistry, Medicinal ; Pharmacology & Pharmacy
语种	英语
WOS记录号	WOS:000243695900003
公开日期	2011-07-08
内容类型	期刊论文
源URL	[http://210.75.237.14/handle/351003/17931]
专题	成都生物研究所_天然产物研究
通讯作者	Gao, XP, Di Ao Pharmaceut Grp, Inst Mat Med, Chengdu 610041, Peoples R China.
推荐引用方式 GB/T 7714	Gao, XP,Li, BG,Jiang, HW,et al. Dioscorea opposita reverses dexamethasone induced insulin resistance[J]. FITOTERAPIA,2007,78(1):12_15.
APA	Gao, XP.,Li, BG.,Jiang, HW.,Liu, FL.,Xu, DY.,...&Gao, XP, Di Ao Pharmaceut Grp, Inst Mat Med, Chengdu 610041, Peoples R China..(2007).Dioscorea opposita reverses dexamethasone induced insulin resistance.FITOTERAPIA,78(1),12_15.
MLA	Gao, XP,et al."Dioscorea opposita reverses dexamethasone induced insulin resistance".FITOTERAPIA 78.1(2007):12_15.