An experimental study on the use of icariin for improving thickness of thin endometrium.

	An experimental study on the use of icariin for improving thickness of thin endometrium.
	X.J. Fang; A.W. Le; Z.H. Wang; X.Y. Dai; T.H. Xiao; R. Zhuo; B.Z. Zhang; Z.L. Xiao
刊名	Genetics and Molecular Research
	2017
文献子类	期刊论文
英文摘要	This study aimed to investigate the effect of icariin (ICA) on thin endometrium in a rat model. To this end, 6- to 8-week- old female Sprague Dawley rats (105) were randomly divided into 7 groups: untreated, vehicle-treated (lavage with NaCl), high-dose ICA (lavage with ICA at 200 mg∙kg -1 ∙day -1 ), medium-dose ICA (lavage ICA at 100 mg∙kg -1 ∙day -1 ), low-dose ICA (lavage with ICA at 50 mg∙kg - 1 ∙day -1 ), sham model (injected with NaCl at uterus horn), and sample group. To induce thin endometrium, rats of all groups (except sham- model) were injected with 95% ethanol via the uterine horn. Each group underwent its respective treatment for 3 estrous cycles, after which 5 rats from each group were sacrificed, and endometrial thickness was measured. The expression of CD31, factor VIII, vascular endothelial growth factor (VEGF), cytokeratin (CK), and vimentin were detected via immunohistochemistry. The results showed that CD31, factor VIII,
URL标识	查看原文
语种	英语
内容类型	期刊论文
源URL	[http://ir.siat.ac.cn:8080/handle/172644/12345]
专题	深圳先进技术研究院_医药所
作者单位	Genetics and Molecular Research
推荐引用方式 GB/T 7714	X.J. Fang,A.W. Le,Z.H. Wang,et al. An experimental study on the use of icariin for improving thickness of thin endometrium.[J]. Genetics and Molecular Research,2017.
APA	X.J. Fang.,A.W. Le.,Z.H. Wang.,X.Y. Dai.,T.H. Xiao.,...&Z.L. Xiao.(2017).An experimental study on the use of icariin for improving thickness of thin endometrium..Genetics and Molecular Research.
MLA	X.J. Fang,et al."An experimental study on the use of icariin for improving thickness of thin endometrium.".Genetics and Molecular Research (2017).