Nanomanipulation of Individual DNA Molecules Covered by Single-Layered Reduced Graphene Oxide Sheets on a Solid Substrate

doi:10.1021/acs.jpcb.7b05175

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	Nanomanipulation of Individual DNA Molecules Covered by Single-Layered Reduced Graphene Oxide Sheets on a Solid Substrate
	Wang, Y ; Shen, Y ; Li, B ; Wang, S ; Zhang, JJ ; Zhang, Y ; Hu, J
刊名	JOURNAL OF PHYSICAL CHEMISTRY B
	2018
卷号	122 期号:2 页码:612-617
关键词	Atomic-force Microscopy Graphite Oxide Mechanical-properties Biaxial Strain Nanosheets Patterns
ISSN号	1520-6106
DOI	10.1021/acs.jpcb.7b05175
文献子类	期刊论文
英文摘要	Nanomanipulation of single DNA molecules has great potential in fundamental genetic research and clinical analysis, and is a good model system for studying the interfacial effects on physiochemical processes, which occur when manipulating the linear DNA molecules with an atomic force microscope (AFM) tip. Here, we demonstrate that AFM nanomanipulation can be carried out on DNA molecules covered by a single-layered reduced graphene oxide sheet. Nanomanipulation, which includes cutting, pushing, and sweeping operations, specific to the covered DNA molecules can be achieved in a well-controlled manner using AFM in the PeakForce Quantitative Nano-Mechanics mode. It was found that the normal force required to cut covered DNA strands is over five times greater than that required for naked strands. This technique provides a distinctive method for the construction of graphene architecture by tailoring the underlying artificial DNA nanostructures.
语种	英语
WOS记录号	WOS:000423140600026
内容类型	期刊论文
源URL	[http://ir.sinap.ac.cn/handle/331007/29079]
专题	上海应用物理研究所_中科院上海应用物理研究所2011-2017年
作者单位	1.Wang, Y 2.Shen, Y 3.Li, B 4.Wang, S 5.Zhang, JJ 6.Zhang, Y 7.Hu, J
推荐引用方式 GB/T 7714	Wang, Y,Shen, Y,Li, B,et al. Nanomanipulation of Individual DNA Molecules Covered by Single-Layered Reduced Graphene Oxide Sheets on a Solid Substrate[J]. JOURNAL OF PHYSICAL CHEMISTRY B,2018,122(2):612-617.
APA	Wang, Y.,Shen, Y.,Li, B.,Wang, S.,Zhang, JJ.,...&Hu, J.(2018).Nanomanipulation of Individual DNA Molecules Covered by Single-Layered Reduced Graphene Oxide Sheets on a Solid Substrate.JOURNAL OF PHYSICAL CHEMISTRY B,122(2),612-617.
MLA	Wang, Y,et al."Nanomanipulation of Individual DNA Molecules Covered by Single-Layered Reduced Graphene Oxide Sheets on a Solid Substrate".JOURNAL OF PHYSICAL CHEMISTRY B 122.2(2018):612-617.