Single Nanochannel-Aptamer-Based Biosensor for Ultrasensitive and Selective Cocaine Detection

CORC > 化学研究所 > 中国科学院化学研究所 > 其它

	Single Nanochannel-Aptamer-Based Biosensor for Ultrasensitive and Selective Cocaine Detection
	Wang, Jian; Hou, Jue; Zhang, Huacheng; Tian, Ye; Jiang, Lei
刊名	ACS APPLIED MATERIALS & INTERFACES
	JAN 17 2018
卷号	10 期号:2 页码:2033-2039
英文摘要	Ultrasensitive and selective detection of molecules at nano or sub-nanomolar level is very important for many areas such as early diagnosis and drug testing. Herein, we report a high-sensitive cocaine sensor based on a single nanochannel coupled with DNA aptamers. The single nanochannel-aptamer-based biosensor can recognize cocaine molecules with an excellent sensitivity and good selectivity. A linear relationship between target cocaine concentration and output ionic current is obtained in a wide concentration range of cocaine from 1 nM to 10 mu M. The cocaine sensor also shows a detection limit down to 1 nM. This study provides a new avenue to develop new nanochannel-aptamer-based biosensors for rapid and ultratrace detection of a variety of illicit drugs.
WOS记录号	WOS:000423140400064
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/38844]
专题	化学研究所_其它
推荐引用方式 GB/T 7714	Wang, Jian,Hou, Jue,Zhang, Huacheng,et al. Single Nanochannel-Aptamer-Based Biosensor for Ultrasensitive and Selective Cocaine Detection[J]. ACS APPLIED MATERIALS & INTERFACES,JAN ,10(2):2033-2039.
APA	Wang, Jian,Hou, Jue,Zhang, Huacheng,Tian, Ye,&Jiang, Lei.(JAN ).Single Nanochannel-Aptamer-Based Biosensor for Ultrasensitive and Selective Cocaine Detection.ACS APPLIED MATERIALS & INTERFACES,10(2),2033-2039.
MLA	Wang, Jian,et al."Single Nanochannel-Aptamer-Based Biosensor for Ultrasensitive and Selective Cocaine Detection".ACS APPLIED MATERIALS & INTERFACES 10.2(JAN ):2033-2039.