Supramolecular Porphyrin Photosensitizers: Controllable Disguise and Photoinduced Activation of. Antibacterial Behavior

	Supramolecular Porphyrin Photosensitizers: Controllable Disguise and Photoinduced Activation of. Antibacterial Behavior
	Chen, Linghui 1; Bai, Haotian 2; Xu, Jiang-Fei 1; Wang, Shu 2; Zhang, Xi 1
刊名	ACS APPLIED MATERIALS & INTERFACES
	2017-04-26
卷号	9 期号:16 页码:13950-13957
关键词	Supramolecular Materials Photodynamic Therapy Host-guest Interactions Cucurbituril Chemistry Antibacterial Control
英文摘要	A series of supramolecular photosensitizers were fabricated from porphyrin derivatives (Por) containing quaternary ammonium groups with cucurbit[7]uril (CB[7]) based on host guest interactions. The antibacterial activity of Por in the dark could be turned off upon binding with CB[7], whereas the antibacterial activity under white-light illumination could be turned on. In addition, its antibacterial efficiency could be greatly enhanced by introducing metal ions. When Pd(II) was introduced into porphyrin, its antibacterial efficiency was enhanced from 40 to 100%. It should be noted that these small molecules showed little to no cytotoxicity toward mammalian cells even at concentrations higher than those under the antibacterial condition studied. This line of research will provide a strategy for germicides consisting of quaternary ammonium groups to fight against bacterial accumulation in the long term and holds huge potential for application in the real world.
语种	英语
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/39027]
专题	化学研究所_有机固体实验室
作者单位	1.Tsinghua Univ, Dept Chem, Key Lab Organ Optoelect & Mol Engn, Beijing 100084, Peoples R China 2.Chinese Acad Sci, Beijing Natl Lab Mol Sci, Inst Chem, Key Lab Organ Solids, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Chen, Linghui,Bai, Haotian,Xu, Jiang-Fei,et al. Supramolecular Porphyrin Photosensitizers: Controllable Disguise and Photoinduced Activation of. Antibacterial Behavior[J]. ACS APPLIED MATERIALS & INTERFACES,2017,9(16):13950-13957.
APA	Chen, Linghui,Bai, Haotian,Xu, Jiang-Fei,Wang, Shu,&Zhang, Xi.(2017).Supramolecular Porphyrin Photosensitizers: Controllable Disguise and Photoinduced Activation of. Antibacterial Behavior.ACS APPLIED MATERIALS & INTERFACES,9(16),13950-13957.
MLA	Chen, Linghui,et al."Supramolecular Porphyrin Photosensitizers: Controllable Disguise and Photoinduced Activation of. Antibacterial Behavior".ACS APPLIED MATERIALS & INTERFACES 9.16(2017):13950-13957.