Enhanced Photothermal Bactericidal Activity of the Reduced Graphene Oxide Modified by Cationic Water-Soluble Conjugated Polymer

	Enhanced Photothermal Bactericidal Activity of the Reduced Graphene Oxide Modified by Cationic Water-Soluble Conjugated Polymer
	Xiao, Linhong 1,3; Sun, Jinhua 1; Liu, Libing 2; Hu, Rong 2; Lu, Huan 2; Cheng, Chungui 1; Huang, Yong 1; Wang, Shu 2; Geng, Jianxin 1
刊名	ACS APPLIED MATERIALS & INTERFACES
	2017-02-15
卷号	9 期号:6 页码:5382-5391
关键词	Graphene Water-soluble Conjugated Polymers Covalent Functionalization Electrostatic Attraction Photothermal Killing Of Bacteria
英文摘要	Surface modification of graphene is extremely important for applications. Here, we report a grafting-through method for grafting water-soluble polythiophenes onto reduced graphene oxide (RGO) sheets. As a result of tailoring of the side chains of the polythiophenes, the modified RGO sheets, that is, RGO-g-P3TOPA and RGO-g-P3TOPS, are positively and negatively charged, respectively. The grafted water-soluble polythiophenes provide the modified RGO sheets with good dispersibility in water and high photothermal conversion efficiencies (ca. 88%). Notably, the positively charged RGO-g-P3TOPA exhibits unprecedentedly excellent photothermal bactericidal activity, because the electrostatic attractions between RGO-g-P3TOPA and Escherichia coli (E. coli) bind them together, facilitating direct heat conduction through their interfaces: the minimum concentration of RGO-g-P3TOPA that kills 100% of E. coli is 2.5 mu g mL(-1), which is only 1/16th of that required for RGO-g-P3TOPS to exhibit a similar bactericidal activity. The direct heat conduction mechanism is supported by zeta-potential measurements and photothermal heating tests, in which the achieved temperature of the RGO-g-P3TOPA suspension (2.5 mu g mL(-1), 32 degrees C) that kills 100% of E. coli is found to be much lower than the thermoablation threshold of bacteria. Therefore, this research demonstrates a novel and superior method that combines photothermal heating effect and electrostatic attractions to efficiently kill bacteria.
语种	英语
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/38244]
专题	化学研究所_有机固体实验室
作者单位	1.Chinese Acad Sci, Tech Inst Phys & Chem, 29 Zhongguancun East Rd, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Beijing Natl Lab Mol Sci, Inst Chem, Key Lab Organ Solids, Beijing 100190, Peoples R China 3.Univ Chinese Acad Sci, 19A Yuquan Rd, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Xiao, Linhong,Sun, Jinhua,Liu, Libing,et al. Enhanced Photothermal Bactericidal Activity of the Reduced Graphene Oxide Modified by Cationic Water-Soluble Conjugated Polymer[J]. ACS APPLIED MATERIALS & INTERFACES,2017,9(6):5382-5391.
APA	Xiao, Linhong.,Sun, Jinhua.,Liu, Libing.,Hu, Rong.,Lu, Huan.,...&Geng, Jianxin.(2017).Enhanced Photothermal Bactericidal Activity of the Reduced Graphene Oxide Modified by Cationic Water-Soluble Conjugated Polymer.ACS APPLIED MATERIALS & INTERFACES,9(6),5382-5391.
MLA	Xiao, Linhong,et al."Enhanced Photothermal Bactericidal Activity of the Reduced Graphene Oxide Modified by Cationic Water-Soluble Conjugated Polymer".ACS APPLIED MATERIALS & INTERFACES 9.6(2017):5382-5391.