Thermal sensitivity and protein anti-adsorption of hydroxypropyl cellulose-g- poly(2-(methacryloyloxy) ethyl phosphorylcholine)

	Thermal sensitivity and protein anti-adsorption of hydroxypropyl cellulose-g- poly(2-(methacryloyloxy) ethyl phosphorylcholine)
	Ci, Jiliang 1,2; Kang, Hongliang 1; Liu, Chenguang 2; He, Aihua 2; Liu, Ruigang 1
刊名	CARBOHYDRATE POLYMERS
	2017-02-10
卷号	157 页码:757-765
关键词	Hydroxypropyl Cellulose Zwitterionic Polymers Self-assembly Thermal Sensitivity Lcst
英文摘要	Zwitterionic graft copolymers, hydroxypropyl cellulose graft poly(2-(methacryloyloxy) ethyl phospho-rylcholine) (HPC-g-PMPC) with well-defined architecture were synthesized by atom transfer radical polymerization (ATRP). The self-assembly behaviors and thermal sensitivity of HPC-g-PMPC copolymers and their correlations with graft density and side chain length were investigated in details. HPC-g-PMPC copolymers can self-assemble into spherical aggregate structure above the critical aggregation concentration (CAC) at room temperature. Meanwhile, the size of the aggregates mainly depended on the graft density. The obtained aggregates were thermal sensitive and their low critical solution temperature (LCST) was efficiently regulated by varying the graft density. Above the LCST, the aggregates were transferred into aggregates with core-shell structure, in which the HPC rich core was stabilized by the PMPC rich shell. The interaction between the HPC-g-PMPC aggregates and BSA was investigated. The results indicated that the anti-adsorption of BSA on the aggregates surface depended on the length and graft density of the PMPC zwitterionic side chains. (C) 2016 Elsevier Ltd. All rights reserved.
语种	英语
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/38027]
专题	化学研究所_高分子物理与化学实验室
作者单位	1.Chinese Acad Sci, Beijing Natl Lab Mol Sci, Inst Chem, State Key Lab Polymer Phys & Chem, Beijing 100190, Peoples R China 2.Qingdao Univ Sci & Technol, Sch Polymer Sci & Engn, Key Lab Rubber Plast, Minist Educ, Qingdao 266042, Peoples R China
推荐引用方式 GB/T 7714	Ci, Jiliang,Kang, Hongliang,Liu, Chenguang,et al. Thermal sensitivity and protein anti-adsorption of hydroxypropyl cellulose-g- poly(2-(methacryloyloxy) ethyl phosphorylcholine)[J]. CARBOHYDRATE POLYMERS,2017,157:757-765.
APA	Ci, Jiliang,Kang, Hongliang,Liu, Chenguang,He, Aihua,&Liu, Ruigang.(2017).Thermal sensitivity and protein anti-adsorption of hydroxypropyl cellulose-g- poly(2-(methacryloyloxy) ethyl phosphorylcholine).CARBOHYDRATE POLYMERS,157,757-765.
MLA	Ci, Jiliang,et al."Thermal sensitivity and protein anti-adsorption of hydroxypropyl cellulose-g- poly(2-(methacryloyloxy) ethyl phosphorylcholine)".CARBOHYDRATE POLYMERS 157(2017):757-765.