Heterocyclic Compounds from the Mushroom Albatrellus confluens and Their Inhibitions against Lipopolysaccharides-Induced B Lymphocyte Cell Proliferation

doi:10.1021/acs.joc.8b01420

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	Heterocyclic Compounds from the Mushroom Albatrellus confluens and Their Inhibitions against Lipopolysaccharides-Induced B Lymphocyte Cell Proliferation
	Zhang, Shuaibing 1,2,3; Huang, Ying 1,2,3; He, Shijun 4; Chen, Heping 1; Wu, Bin 1; Li, Shanyong 2,3; Zhao, Zhenzhu 2,3; Li, Zhenghui 1; Wang, Xian 1; Zuo, Jianping 4
刊名	JOURNAL OF ORGANIC CHEMISTRY
	2018-09-07
卷号	83 期号:17 页码:10158-10165
ISSN号	0022-3263
DOI	10.1021/acs.joc.8b01420
英文摘要	Eight hetereocyclic compounds conflamides B-I with an unprecedented skeleton and their precursor conflamide A were isolated from the mushroom Albatrellus confluens. Their structures and absolute configurations were determined by use of NMR studies, total synthesis, and calculated ECD spectra. Conflamides D and E were found to exhibit potent inhibition against LPS-induced B lymphocyte cell proliferation with IC50 values 1.48 and 5.71 mu M, respectively.
资助项目	National Key Research and Development Program of China[2017YFC1704007] ; National Natural Science Foundation of China[81773590] ; National Natural Science Foundation of China[81561148013] ; Thailand Research Fund[DBGS980002] ; Key Projects of Technological Innovation of Hubei Province[2016ACA138] ; Fundamental Research Funds for the Central University ; South-Central University for Nationalities[CZP18005] ; South-Central University for Nationalities[CZQ17010] ; South-Central University for Nationalities[CZQ17008] ; South-Central University for Nationalities[CZT18014] ; South-Central University for Nationalities[CZT18013]
WOS研究方向	Chemistry
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000444364600049
资助机构	National Key Research and Development Program of China ; National Natural Science Foundation of China ; Thailand Research Fund ; Key Projects of Technological Innovation of Hubei Province ; Fundamental Research Funds for the Central University ; South-Central University for Nationalities
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/62420]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
通讯作者	Zuo, Jianping; Feng, Tao; Liu, Jikai
作者单位	1.South Cent Univ Nationalities, Sch Pharmaceut Sci, Wuhan 430074, Hubei, Peoples R China 2.Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Shuaibing,Huang, Ying,He, Shijun,et al. Heterocyclic Compounds from the Mushroom Albatrellus confluens and Their Inhibitions against Lipopolysaccharides-Induced B Lymphocyte Cell Proliferation[J]. JOURNAL OF ORGANIC CHEMISTRY,2018,83(17):10158-10165.
APA	Zhang, Shuaibing.,Huang, Ying.,He, Shijun.,Chen, Heping.,Wu, Bin.,...&Liu, Jikai.(2018).Heterocyclic Compounds from the Mushroom Albatrellus confluens and Their Inhibitions against Lipopolysaccharides-Induced B Lymphocyte Cell Proliferation.JOURNAL OF ORGANIC CHEMISTRY,83(17),10158-10165.
MLA	Zhang, Shuaibing,et al."Heterocyclic Compounds from the Mushroom Albatrellus confluens and Their Inhibitions against Lipopolysaccharides-Induced B Lymphocyte Cell Proliferation".JOURNAL OF ORGANIC CHEMISTRY 83.17(2018):10158-10165.