A Novel Flavonoid Glucoside from the Fruits of Lycium ruthenicun | |
Qi, Jing-Jing1,2; Yan, Yong-Ming3; Cheng, Li-Zhi3; Liu, Bao-Hua3; Qin, Fu-Ying2,3; Cheng, Yong-Xian1,2,3,4 | |
刊名 | MOLECULES
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2018-02-01 | |
卷号 | 23期号:2页码:325 |
关键词 | Lycium Ruthenicun Flavonoid Ruthenicunoid a Sirt1 |
ISSN号 | 1420-3049 |
DOI | 10.3390/molecules23020325 |
英文摘要 | A novel flavonoid glucoside, ruthenicunoid A (1), together with eight known substances, were isolated from the fruits of Lycium ruthenicun Murr. Their structures were elucidated by extensive spectroscopic data and chemical methods. Especially, the absolute configuration of glucose residue in 1 was assigned by acid hydrolysis followed by derivatization and GC analysis. Biological evaluation towards Sirtuin 1 (SIRT1) found that compounds 1 and 2 exhibit inhibitory activity against SIRT1 in a concentration-dependent manner, indicating its potential on SIRT1-associated disorders. |
语种 | 英语 |
WOS记录号 | WOS:000426436300105 |
内容类型 | 期刊论文 |
源URL | [http://ir.kib.ac.cn/handle/151853/60442] ![]() |
专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | 1.Yunnan Univ Tradit Chinese Med, Sch Pharm, Kunming 650500, Yunnan, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 3.Shenzhen Univ Hlth Sci Ctr, Sch Med, Sch Pharmaceut Sci, Guangdong Key Lab Genome Stabil & Dis Prevent, Shenzhen 518060, Peoples R China 4.Henan Univ Chinese Med, Sch Pharm, Zhengzhou 450008, Henan, Peoples R China |
推荐引用方式 GB/T 7714 | Qi, Jing-Jing,Yan, Yong-Ming,Cheng, Li-Zhi,et al. A Novel Flavonoid Glucoside from the Fruits of Lycium ruthenicun[J]. MOLECULES,2018,23(2):325. |
APA | Qi, Jing-Jing,Yan, Yong-Ming,Cheng, Li-Zhi,Liu, Bao-Hua,Qin, Fu-Ying,&Cheng, Yong-Xian.(2018).A Novel Flavonoid Glucoside from the Fruits of Lycium ruthenicun.MOLECULES,23(2),325. |
MLA | Qi, Jing-Jing,et al."A Novel Flavonoid Glucoside from the Fruits of Lycium ruthenicun".MOLECULES 23.2(2018):325. |
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