Labdane and Tetranorlabdane Diterpenoids from Botryosphaeria sp MHF, an Endophytic fungus of Maytenus hookeri
Yuan, Lin1,2; Zhao, Pei-Ji1; Ma, Juan1; Lu, Chun-Hua1; Shen, Yue-Mao1
刊名HELVETICA CHIMICA ACTA
2009
卷号92期号:6页码:1118-1125
关键词Cyclopeptide Agina Japonica Sajaponicin a Sajaponicin b Structure
ISSN号0018-019X
文献子类Article
英文摘要Five new diterpenoids, named botryosphaerins A-E (1-5, resp.), including one labdane and four tetranorlabdane diterpenes, were isolated from the solid culture of the endophytic fungal strain Botryosphaeria sp. MHF of Maytenus hookeri, together with seven known diterpenoids, namely 13,14,15,16-tetranorlabd-7-ene-19,6 beta: 12,17-diolide (6), acrostalidic acid (7), acrostalic acid (8), agathic acid (9). isocupressic acid (10), LL-Z1271 beta (11), and CJ-14445 (12). The structures of all compounds were established on the basis of comprehensive spectroscopic studies. The relative configurations of 1 and 2 were determined by single-crystal X-ray diffraction analyses. All compounds except 4 were evaluated for their inhibitory activities against several pathogenic bacterial and fungal strains. However, only compound 12 showed significant inhibitions against Candida albicans, Saccharomyces cerevisiae, and Penicillium avellaneum UC-4376 with nystatin as a positive control.
学科主题Chemistry, Multidisciplinary
WOS关键词STREPTOMYCES-SP ; OIDIOLACTONE-C ; METABOLITES ; OIDIODENDRON ; ACID
WOS研究方向Chemistry
语种英语
WOS记录号WOS:000267738800011
公开日期2012-03-21
内容类型期刊论文
源URL[http://ir.kib.ac.cn:8080/handle/151853/4852]  
专题昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Kunming Univ, Sch Chem, Kunming 650031, Peoples R China
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Yuan, Lin,Zhao, Pei-Ji,Ma, Juan,et al. Labdane and Tetranorlabdane Diterpenoids from Botryosphaeria sp MHF, an Endophytic fungus of Maytenus hookeri[J]. HELVETICA CHIMICA ACTA,2009,92(6):1118-1125.
APA Yuan, Lin,Zhao, Pei-Ji,Ma, Juan,Lu, Chun-Hua,&Shen, Yue-Mao.(2009).Labdane and Tetranorlabdane Diterpenoids from Botryosphaeria sp MHF, an Endophytic fungus of Maytenus hookeri.HELVETICA CHIMICA ACTA,92(6),1118-1125.
MLA Yuan, Lin,et al."Labdane and Tetranorlabdane Diterpenoids from Botryosphaeria sp MHF, an Endophytic fungus of Maytenus hookeri".HELVETICA CHIMICA ACTA 92.6(2009):1118-1125.
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