Antioxidant properties of two gallotannins isolated from the leaves of Pistacia weinmannifolia

doi:10.1016/j.bbagen.2005.04.015

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Antioxidant properties of two gallotannins isolated from the leaves of Pistacia weinmannifolia
	Zhao, XY ; Sun, HD; Hou, AJ ; Zhao, QS; Wei, TT ; Xin, WJ
刊名	BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
	2005-08-30
卷号	1725 期号:1 页码:103-110
关键词	Pistacia Weinmannifolia Pistafolin a Pistafolin b Gallotannin Antioxidant
ISSN号	0304-4165
DOI	10.1016/j.bbagen.2005.04.015
文献子类	Article
英文摘要	Joistacia weinmannifolia J. Poisson ex Franch (Anacardiaccae) is a shrub or arbor widely found in Yunnan province of China and its leaves are used as traditional Chinese medicine by herbalists. The leaves of R weinmannifolia are rich in phenolic compounds, among which two novel gallotannins, Pistafolin A and Pistafolin B, are identified. In the present investigation, the antioxidant efficiency of Pistafolin A and Pistafolin B in preventing lipid, protein and DNA from reactive oxygen species-mediated damage was studied. Both Pistafolin A and Pistafolin B inhibited the peroxyl-radical induced lipid peroxidation Of L-alpha-phosphatidylcholine liposomes dose-dependently and prevented the bovine serum albumin from peroxyl-induced oxidative damage. Pistafolin A and Pistafolin B also inhibited copper (II)-1,10-phenanthroline complex-induced DNA oxidative damage. Both Pistafolin A and Pistafolin B scavenged the hydrophilic 2,2 '-azinobis(3-ethylbenzothiozoline-6-sulphonic acid) diammonium salt-free radicals and the hydrophobic 1,1-dipheny-2-picrylhydrazyl radicals effectively, suggesting they may act as hydrogen donating antioxidants. The protective effects of the two gallotannins against oxidative damage of biomacromolecules were due to their strong free radical scavenging ability. Pistafolin A with three galloyl moieties showed stronger antioxidant ability than Pistafolin B with two galloyl moieties. (c) 2005 Elsevier B.V. All rights reserved.
学科主题	Biochemistry & Molecular Biology ; Biophysics
WOS关键词	PHENOLIC-COMPOUNDS ; LIPID-PEROXIDATION ; POLYPHENOLS ; DAMAGE ; DNA ; RADICALS ; TEA ; MECHANISMS ; PREVENTION ; PROTECTION
WOS研究方向	Biochemistry & Molecular Biology ; Biophysics
语种	英语
WOS记录号	WOS:000231664500012
公开日期	2012-03-21
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn:8080/handle/151853/4162]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Inst Biophys, Ctr Struct & Mol Biol, Beijing 100101, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 3.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Zhao, XY,Sun, HD,Hou, AJ,et al. Antioxidant properties of two gallotannins isolated from the leaves of Pistacia weinmannifolia[J]. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS,2005,1725(1):103-110.
APA	Zhao, XY,Sun, HD,Hou, AJ,Zhao, QS,Wei, TT,&Xin, WJ.(2005).Antioxidant properties of two gallotannins isolated from the leaves of Pistacia weinmannifolia.BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS,1725(1),103-110.
MLA	Zhao, XY,et al."Antioxidant properties of two gallotannins isolated from the leaves of Pistacia weinmannifolia".BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1725.1(2005):103-110.