Mixed lignan-neolignans from Tarenna attenuata | |
Yang, Xian-Wen; Zhao, Pei-Ji; Ma, Yan-Lin; Xiao, Hai-Tao; Zuo, Yi-Qing; He, Hong-Ping; Li, Ling; Hao, Xiao-Jiang | |
刊名 | JOURNAL OF NATURAL PRODUCTS |
2007-04-01 | |
卷号 | 70期号:4页码:521-525 |
关键词 | Medicinal-plants Constituents |
ISSN号 | 0163-3864 |
DOI | 10.1021/np0603931 |
文献子类 | Article |
英文摘要 | Six new mixed lignan-neolignans and 20 known compounds were isolated from the whole plant of Tarenna attenuata. By analysis of physical and spectroscopic data, the structures of the new compounds were elucidated as (1R,5R,6R)-6-{4-O-[2-(1-(4-hydroxy-3-methoxyphenyl))glycerol]-3,5-dimethoxyphenyl}-3,7-dioxabicyclo[3.3.0]octan-2-one (1), 5' '-methoxyhedyotisol A (2), 4' '-O-(8-guaiacylglycerol)buddlenol A (3), 5' '-methoxy-4' '-O-(8-guaiacylglycerol)buddlenol A (4), 4,6-dimethoxy-5-hydroxy-3-hydroxymethyl-2-(3,4,5-trimethoxyphenyl)-2,3-dihydrobenzofuran (5), and 7-O-ethylguaiacylglycerol (6). Compounds 1, 5, 6, and 8 showed potent antioxidant activities against H2O2-induced impairment in PC12 cells, and compounds 1, 2, 5, and 7 scavenged DPPH radical strongly with IC50 values of 72, 87, 45, and 55 mu M, respectively. |
学科主题 | Plant Sciences ; Chemistry ; Medicinal ; Pharmacology & Pharmacy |
WOS关键词 | MEDICINAL-PLANTS ; CONSTITUENTS |
WOS研究方向 | Plant Sciences ; Pharmacology & Pharmacy |
语种 | 英语 |
WOS记录号 | WOS:000246007200005 |
公开日期 | 2011-11-24 |
内容类型 | 期刊论文 |
源URL | [http://ir.kib.ac.cn:8080/handle/151853/2085] |
专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | 1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China 2.Second Mil Med Univ, Dept Nat Prod Chem, Sch Pharm, Shanghai 200433, Peoples R China 3.Kunming Med Coll, Yunnan Pharmacol Labs Nat Prod, Kunming 650031, Peoples R China 4.Guiyang Med Coll, Sch Pharm, Guiyang 550004, Peoples R China |
推荐引用方式 GB/T 7714 | Yang, Xian-Wen,Zhao, Pei-Ji,Ma, Yan-Lin,et al. Mixed lignan-neolignans from Tarenna attenuata[J]. JOURNAL OF NATURAL PRODUCTS,2007,70(4):521-525. |
APA | Yang, Xian-Wen.,Zhao, Pei-Ji.,Ma, Yan-Lin.,Xiao, Hai-Tao.,Zuo, Yi-Qing.,...&Hao, Xiao-Jiang.(2007).Mixed lignan-neolignans from Tarenna attenuata.JOURNAL OF NATURAL PRODUCTS,70(4),521-525. |
MLA | Yang, Xian-Wen,et al."Mixed lignan-neolignans from Tarenna attenuata".JOURNAL OF NATURAL PRODUCTS 70.4(2007):521-525. |
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