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	Effects of Ionic Dependence of DNA Persistence Length on the DNA Condensation at Room Temperature
	Hu, L; Liu, YH (reprint author), Chinese Acad Sci, Inst Theoret Phys, State Key Lab Theoret Phys, Beijing 100190, Peoples R China.; Liu, YH (reprint author), Guizhou Univ, Coll Anim Sci, Minist Educ, Key Lab Anim Genet Breeding & Reprod Plateau Mt R, Guiyang 550025, Peoples R China.; Liu, YH (reprint author), Guizhou Univ, Coll Sci, Guiyang 550025, Peoples R China.; Xu, HQ; Mao, W; Liu, YH
刊名	COMMUNICATIONS IN THEORETICAL PHYSICS
	2016
卷号	65期号:5页码:639-644
关键词	Dna Condensation Monte Carlo Simulation Persistence Length Multivalent Cation
英文摘要	DNA persistence length is a key parameter for quantitative interpretation of the conformational properties of DNA and related to the bending rigidity of DNA. A series of experiments pointed out that, in the DNA condensation process by multivalent cations, the condensed DNA takes elongated coil or compact globule states and the population of the compact globule states increases with an increase in ionic concentration. At the same time, single molecule experiments carried out in solution with multivalent cations (such as spermidine, spermine) indicated that DNA persistence length strongly depends on the ionic concentration. In order to revolve the effects of ionic concentration dependence of persistence length on DNA condensation, a model including the ionic concentration dependence of persistence length and strong correlation of multivalent cation on DNA is provided. The autocorrelation function of the tangent vectors is found as an effective way to detect the ionic concentration dependence of toroidal conformations. With an increase in ion concentration, the first periodic oscillation contained in the autocorrelation function shifts, the number of segment contained in the first periodic oscillation decreases gradually. According to the experiments, the average long-axis length is defined to estimate the ionic concentration dependence of condensation process further. The relation between long-axis length and ionic concentration matches the experimental results qualitatively.
学科主题	Physics
语种	英语
内容类型	期刊论文
源URL	[http://ir.itp.ac.cn/handle/311006/21672]
专题	理论物理研究所_理论物理所1978-2010年知识产出
通讯作者	Liu, YH (reprint author), Chinese Acad Sci, Inst Theoret Phys, State Key Lab Theoret Phys, Beijing 100190, Peoples R China.; Liu, YH (reprint author), Guizhou Univ, Coll Anim Sci, Minist Educ, Key Lab Anim Genet Breeding & Reprod Plateau Mt R, Guiyang 550025, Peoples R China.; Liu, YH (reprint author), Guizhou Univ, Coll Sci, Guiyang 550025, Peoples R China.
推荐引用方式 GB/T 7714	Hu, L,Liu, YH ,Liu, YH ,et al. Effects of Ionic Dependence of DNA Persistence Length on the DNA Condensation at Room Temperature[J]. COMMUNICATIONS IN THEORETICAL PHYSICS,2016,65(5):639-644.
APA	Hu, L.,Liu, YH .,Liu, YH .,Liu, YH .,Xu, HQ.,...&Liu, YH.(2016).Effects of Ionic Dependence of DNA Persistence Length on the DNA Condensation at Room Temperature.COMMUNICATIONS IN THEORETICAL PHYSICS,65(5),639-644.
MLA	Hu, L,et al."Effects of Ionic Dependence of DNA Persistence Length on the DNA Condensation at Room Temperature".COMMUNICATIONS IN THEORETICAL PHYSICS 65.5(2016):639-644.

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