Molecular phylogeny of coronaviruses including human SARS-CoV | |
Gao, L; Qi, J; Wei, HB; Sun, YG; Hao, BL; Hao, BL , Fudan Univ, T Life Res Ctr, Shanghai 200433, Peoples R China. | |
刊名 | CHINESE SCIENCE BULLETIN |
2003 | |
卷号 | 48期号:12页码:1170-1174 |
关键词 | Acute Respiratory Syndrome Sequence |
ISSN号 | 1001-6538 |
英文摘要 | Phylogenetic tree of coronaviruses (CoVs) including the human SARS-associated virus is reconstructed from complete genomes by using our newly developed K-string composition approach. The relation of the human SARS-CoV to other coronaviruses, i.e. the rooting of the tree is suggested by choosing an appropriate outgroup. SARS-CoV makes a separate group closer but still distant from G2 (CoVs in mammalian host). The relation between different isolates of the human SARS virus is inferred by first constructing an ultrametric distance matrix from counting sequence variations in the genomes. The resulting tree is consistent with clinic relations between the SARS-CoV isolates. In addition to a larger variety of coronavirus genomes these results provide phylogenetic knowledge based on independent novel methodology as compared to recent phylogenetic studies on SARS-CoV. |
学科主题 | Physics |
URL标识 | 查看原文 |
WOS记录号 | WOS:000184249300002 |
公开日期 | 2012-08-29 |
内容类型 | 期刊论文 |
源URL | [http://ir.itp.ac.cn/handle/311006/13280] |
专题 | 理论物理研究所_理论物理所1978-2010年知识产出 |
通讯作者 | Hao, BL , Fudan Univ, T Life Res Ctr, Shanghai 200433, Peoples R China. |
推荐引用方式 GB/T 7714 | Gao, L,Qi, J,Wei, HB,et al. Molecular phylogeny of coronaviruses including human SARS-CoV[J]. CHINESE SCIENCE BULLETIN,2003,48(12):1170-1174. |
APA | Gao, L,Qi, J,Wei, HB,Sun, YG,Hao, BL,&Hao, BL , Fudan Univ, T Life Res Ctr, Shanghai 200433, Peoples R China..(2003).Molecular phylogeny of coronaviruses including human SARS-CoV.CHINESE SCIENCE BULLETIN,48(12),1170-1174. |
MLA | Gao, L,et al."Molecular phylogeny of coronaviruses including human SARS-CoV".CHINESE SCIENCE BULLETIN 48.12(2003):1170-1174. |
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