Cortical Inhibition Related to Aging and Mental Disorders
Chen Wei-Ying2,3; Li Sheng-Guang1,2; Zhang Tao1,2,3; Zhang T(张弢)
刊名PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS
2018-04-01
卷号45期号:4页码:401-408
关键词inter-cortical inhibition intra-cortical inhibition center-surround suppression motion repulsion brain dysfunction
ISSN号1000-3282
DOI10.16476/j.pibb.2017.0391
其他题名Cortical Inhibition Related to Aging and Mental Disorders
产权排序2
文献子类Article
英文摘要The neural network of our brain processes all kinds of information through excitatory and inhibitory synapses. Although there are less inhibitory neurons in the brain, they are extremely important in regulating information processing and neuronal plasticity. Further more, various of brain dysfunctions are related to the disfunction of inhibitory system. Inter-cortical inhibition, which includes feedforward and feedback projections, mediates the inhibitory effects between different brain areas. Intra-cortical inhibition, or mutual inhibition, mediates inhibitory interactions between neurons nearby but with different preferences. In this review, we introduced the behavioral performance of two kinds of inbitiory mechanisms, using center-surround suppression and motion repulsion paradigm as examples. Then we related the changes of cortical inhibition to aging and two typical mental disorders.
WOS关键词CENTER-SURROUND ANTAGONISM ; CLASSICAL RECEPTIVE-FIELD ; VISUAL-CORTEX ; BIPOLAR DISORDER ; MOTION PERCEPTION ; DIRECTION REPULSION ; GABA NEURONS ; SCHIZOPHRENIA ; NETWORK ; SUPPRESSION
WOS研究方向Biochemistry & Molecular Biology ; Biophysics
语种英语
WOS记录号WOS:000430898100002
资助机构National Natural Science Foundation of China(31271175)
内容类型期刊论文
源URL[http://ir.psych.ac.cn/handle/311026/25696]  
专题心理研究所_脑与认知科学国家重点实验室
心理研究所_认知与发展心理学研究室
通讯作者Zhang T(张弢)
作者单位1.State Key Lab Brain & Cognit Sci, Beijing 100101, Peoples R China
2.Chinese Acad Sci, Inst Psychol, Beijing 100101, Peoples R China
3.Univ Chinese Acad Sci, Dept Psychol, Beijing 100101, Peoples R China
推荐引用方式
GB/T 7714
Chen Wei-Ying,Li Sheng-Guang,Zhang Tao,et al. Cortical Inhibition Related to Aging and Mental Disorders[J]. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,2018,45(4):401-408.
APA Chen Wei-Ying,Li Sheng-Guang,Zhang Tao,&张弢.(2018).Cortical Inhibition Related to Aging and Mental Disorders.PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,45(4),401-408.
MLA Chen Wei-Ying,et al."Cortical Inhibition Related to Aging and Mental Disorders".PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 45.4(2018):401-408.
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