Label-free protein detection using terahertz time-domain spectroscopy | |
Han, Xiaohui1,2; Yan, Shihan2; Wei, Dongshan2; Cui, Hong-Liang1,2; Du, Chunlei2 | |
2016 | |
会议日期 | October 10, 2016 - October 12, 2016 |
会议地点 | Chongqing, China |
DOI | 10.1364/ISUPTW.2016.IT2A.20 |
通讯作者 | Cui, Hong-Liang (hcui@jlu.edu.cn) |
英文摘要 | Quantitative analysis of protein is the basics to understand the mechanisms of biological processes in terms of the interactions, activities and regulation of the underlying proteins. Protein immunoblot belongs to the common methods to determinate protein content and includes several complicated and time-consuming steps. In the proposed method the membrane made of nitrocellulose after being moved on proteins is directly scanned by using terahertz time domain spectroscopy system (THz-TDS) to qualitatively and quantitatively protein species and quantity. It does not require the detected proteins being labeled by corresponding antibodies, which is free from tedious interlocking steps and much time is saved. Six different kinds of proteins under investigation can be distinguished by refractive index extracted from THz transmission spectrum. © OSA 2016. |
会议录 | International Symposium on Ultrafast Phenomena and Terahertz Waves, ISUPTW 2016 |
语种 | 英语 |
WOS记录号 | WOS:000426743300006 |
内容类型 | 会议论文 |
源URL | [http://119.78.100.138/handle/2HOD01W0/4846] |
专题 | 太赫兹技术研究中心 微纳制造与系统集成研究中心 |
作者单位 | 1.College of Instrumentation and Electrical Engineering, Jilin University, Changchun, Jilin; 130061, China; 2.Chongqing Key laboratory of Multi-Scale manufacturing Technology, Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing; 400714, China |
推荐引用方式 GB/T 7714 | Han, Xiaohui,Yan, Shihan,Wei, Dongshan,et al. Label-free protein detection using terahertz time-domain spectroscopy[C]. 见:. Chongqing, China. October 10, 2016 - October 12, 2016. |
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