3D nanopore shape control by current-stimulus dielectric breakdown

doi:10.1063/1.4960636

CORC > 重庆绿色智能技术研究院 > 中国科学院重庆绿色智能技术研究院 > 精准医疗单分子诊断技术研究中心

	3D nanopore shape control by current-stimulus dielectric breakdown
	Ying, Cuifeng 1,2,3; Zhang, Yuechuan 2; Feng, Yanxiao 2; Zhou, Daming2 ; Wang, Deqiang1,2 ; Xiang, Yinxiao 1; Zhou, Wenyuan 1,3; Chen, Yongsheng 4; Du, Chunlei2 ; Tian, Jianguo 1,3
刊名	APPLIED PHYSICS LETTERS
	2016-08-08
卷号	109 期号:6 页码:5
ISSN号	0003-6951
DOI	10.1063/1.4960636
通讯作者	Wang, DQ ; Tian, JG (reprint author), Nankai Univ, Sch Phys, Key Lab Weak Light Nonlinear Photon, Minist Educ, Tianjin 300071, Peoples R China. ; Wang, DQ (reprint author), Chinese Acad Sci, Chongqing Inst Green & Intelligent Technol, Chongqing Key Lab Multiscale Mfg Technol, Chongqing 400714, Peoples R China. ; Tian, JG (reprint author), Nankai Univ, Collaborat Innovat Ctr Biotherapy, 94 Weijin Rd, Tianjin 300071, Peoples R China.
英文摘要	We propose a simple and cost-effect method, current-stimulus dielectric breakdown, to manipulate the 3D shapes of the nanochannels in 20-nm-thick SiNx membranes. Besides the precise control of nanopore size, the cone orientation can be determined by the pulse polarity. The cone angle of nanopores can be systematically tuned by simply changing the stimulus pulse waveform, allowing the gradual shape control from conical to obconical. After they are formed, the cone angle of these nanopores can be further tuned in a certain range by adjusting the widening pulse. Such size and 3D shape controllable abiotic nanopores can construct a constriction in the nanochannel and hence produce a sub-nm "sensing zone" to suit any desired bio-sensing or precise DNA sequencing. Using these conical nanopores, 20-nt ssDNA composed of homopolymers (poly(dA)(20), poly(dC)(20), and poly(dT)(20)) can be clearly differentiated by their ionic current signals. Published by AIP Publishing.
资助项目	International Science & Technology Cooperation Program of China[2013DFA51430] ; National Key Scientific Instrument and Equipment Development Project of China[2013YQ030595] ; National Natural Science Foundations of China[31527801] ; National Natural Science Foundations of China[61471336] ; Joint-Scholar of West Light Foundation of the Chinese Academy of Sciences
WOS研究方向	Physics
语种	英语
出版者	AMER INST PHYSICS
WOS记录号	WOS:000383183600042
内容类型	期刊论文
源URL	[http://119.78.100.138/handle/2HOD01W0/2777]
专题	精准医疗单分子诊断技术研究中心微纳制造与系统集成研究中心
通讯作者	Wang, Deqiang; Tian, Jianguo
作者单位	1.Nankai Univ, Sch Phys, Key Lab Weak Light Nonlinear Photon, Minist Educ, Tianjin 300071, Peoples R China 2.Chinese Acad Sci, Chongqing Inst Green & Intelligent Technol, Chongqing Key Lab Multiscale Mfg Technol, Chongqing 400714, Peoples R China 3.Nankai Univ, Collaborat Innovat Ctr Biotherapy, 94 Weijin Rd, Tianjin 300071, Peoples R China 4.Nankai Univ, Inst Polymer Chem, Key Lab Funct Polymer Mat, Ctr Nanoscale Sci & Technol,Coll Chem, Tianjin 300071, Peoples R China
推荐引用方式 GB/T 7714	Ying, Cuifeng,Zhang, Yuechuan,Feng, Yanxiao,et al. 3D nanopore shape control by current-stimulus dielectric breakdown[J]. APPLIED PHYSICS LETTERS,2016,109(6):5.
APA	Ying, Cuifeng.,Zhang, Yuechuan.,Feng, Yanxiao.,Zhou, Daming.,Wang, Deqiang.,...&Tian, Jianguo.(2016).3D nanopore shape control by current-stimulus dielectric breakdown.APPLIED PHYSICS LETTERS,109(6),5.
MLA	Ying, Cuifeng,et al."3D nanopore shape control by current-stimulus dielectric breakdown".APPLIED PHYSICS LETTERS 109.6(2016):5.