Synthesis of water-soluble quaternized chitosans and their antitumor activity

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 中科院海岸带环境过程与生态修复重点实验室 > 污染过程与控制实验室

	Synthesis of water-soluble quaternized chitosans and their antitumor activity
	Dong,Fang ; Xue,Qinzhao ; Liu,Jingli ; Ren,Jianming ; Guo,Zhanyong
	2010
会议日期	2010-06-18
会议地点	.
关键词	Bioinformatics Chitin Chitosan Hydrogels Hydrogen Peroxide Multilayers Oxidation
通讯作者	Dong,F.
英文摘要	water-soluble low-molecular-weight chitosan(LCTS) was prepared by hydrogen peroxide oxidation method and their quaternized derivatives(QLCTS) was also synthesized using previous methods. Their antitumor activity was studied, and the results showed that the LMW and its quaternized derivatives inhibited the growth of pancreatic carcinoma cell strain PANC-1 in vitro, and the inhibitory rate reached 59.2%. © 2010 IEEE.
产权排序	(1) Yantai Institute of Coastal Zone Research for Sustainable Development, CAS, Yantai, 264003, China; (2) Institute of Oceanology, CAS, Qingdao, 266071, China; (3) Graduate School of the Chinese Academy of Sciences, Beijing, China
会议录	2010 4th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2010
会议录出版者	IEEE Computer Society, 445 Hoes Lane - P.O.Box 1331, Piscataway, NJ 08855-1331, United States
学科主题	有机化学
语种	英语
URL标识	查看原文
ISBN号	ISBN-13:9781424447138
内容类型	会议论文
源URL	[http://ir.yic.ac.cn/handle/133337/4780]
专题	烟台海岸带研究所_污染过程与控制实验室
推荐引用方式 GB/T 7714	Dong,Fang,Xue,Qinzhao,Liu,Jingli,et al. Synthesis of water-soluble quaternized chitosans and their antitumor activity[C]. 见:. .. 2010-06-18.