One-step preparation of zirconia coated silica microspheres and modification with D-fructose 1, 6-bisphosphate as stationary phase for hydrophilic interaction chromatography

	One-step preparation of zirconia coated silica microspheres and modification with D-fructose 1, 6-bisphosphate as stationary phase for hydrophilic interaction chromatography
	Guan, Yafeng 2; Song, Zhihua 1,2; Duan, Chunfeng 2; Shi, Meng 1,2; Li, Shenghong 2
刊名	JOURNAL OF CHROMATOGRAPHY A
	2017-11-03
卷号	1522 页码:30-37
关键词	ZrO2 coated SiO2 Surfactant-free D-Fructose 1 6-Bisphosphate Hydrophilic interaction chromatography
英文摘要	In this study, ZrO2 layer coated silica microspheres (ZrO2/SiO2) were successfully prepared by a facile one-step surfactant-free hydrothermal route under low pH condition. The synthesized ZrO2/SiO2 material was then modified with D-fructose 1, 6-bisphosphate (FDP) to improve the chromatographic separation property of the material. Fused-silica capillary columns were prepared with the modified material for evaluation. Phenolic, nucleobases and alkaloids compounds in hydrophilic interaction chromatographic (HILIC) mode showed symmetrical peaks. The FDP-ZrO2/SiO2 stationary phase showed better performance than ZrO2/SiO2 packing material and demonstrated great potential for application in HILIC mode. (C) 2017 Elsevier B.V. All rights reserved.
WOS标题词	Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences
类目[WOS]	Biochemical Research Methods ; Chemistry, Analytical
研究领域[WOS]	Biochemistry & Molecular Biology ; Chemistry
关键词[WOS]	HPLC SEPARATION ; BONDED SILICA ; PERFORMANCE ; SPHERES ; NANOPARTICLES ; RETENTION
收录类别	SCI
语种	英语
WOS记录号	WOS:000413383200005
内容类型	期刊论文
源URL	[http://cas-ir.dicp.ac.cn/handle/321008/149704]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Univ Chinese Acad Sci, Beijing 100039, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, CAS Key Lab Separat Sci Analyt Chem, 457 Zhongshan Rd, Dalian 116023, Peoples R China
推荐引用方式 GB/T 7714	Guan, Yafeng,Song, Zhihua,Duan, Chunfeng,et al. One-step preparation of zirconia coated silica microspheres and modification with D-fructose 1, 6-bisphosphate as stationary phase for hydrophilic interaction chromatography[J]. JOURNAL OF CHROMATOGRAPHY A,2017,1522:30-37.
APA	Guan, Yafeng,Song, Zhihua,Duan, Chunfeng,Shi, Meng,&Li, Shenghong.(2017).One-step preparation of zirconia coated silica microspheres and modification with D-fructose 1, 6-bisphosphate as stationary phase for hydrophilic interaction chromatography.JOURNAL OF CHROMATOGRAPHY A,1522,30-37.
MLA	Guan, Yafeng,et al."One-step preparation of zirconia coated silica microspheres and modification with D-fructose 1, 6-bisphosphate as stationary phase for hydrophilic interaction chromatography".JOURNAL OF CHROMATOGRAPHY A 1522(2017):30-37.