Perineural dexamethasone does not enhance the analgesic efficacy of ultrasound-guided subcostal transversus abdominis plane block during laparoscopic cholecystectomy

doi:10.1016/S1499-3872(16)60086-3

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	Perineural dexamethasone does not enhance the analgesic efficacy of ultrasound-guided subcostal transversus abdominis plane block during laparoscopic cholecystectomy
	Huang, SH; Lu, J; Gan, HY; Li, Y; Peng, YG; Wang, SK; Wang, SK (reprint author), Lanzhou Univ, Hosp 2, Dept Orthoped, Lanzhou 730030, Peoples R China.
刊名	HEPATOBILIARY & PANCREATIC DISEASES INTERNATIONAL
	2016-10-15
卷号	15 期号:5 页码:540-545
关键词	ultrasonography local analgesic laparoscopic cholecystectomy dexamethasone
ISSN号	1499-3872
DOI	10.1016/S1499-3872(16)60086-3
文献子类	Article
英文摘要	BACKGROUND: Ultrasound-guided transversus abdominis plane (TAP) block is an adjunct therapy to provide effective postoperative analgesia in abdominal surgical procedures. Dexamethasone is a supplement agent that can improve the efficacy of local anesthesia. However, information about its additive effect is limited. This study aimed to compare the analgesic efficiency using ultrasound-guided TAP block with and without perineural dexamethasone for patients who underwent laparoscopic cholecystectomy. METHODS: Sixty patients who underwent laparoscopic cholecystectomy were randomly divided into three groups: group I, controls; group II, TAP; and group III, TAP+perineural dexamethasone supplement. The requirement of additional analgesia and the first-time request of rescue-analgesia were recorded after operation and the numerical rating scale was evaluated at specific intervals. RESULTS: Compared to group I, the first-time requirement of rescue-analgesia in groups II and III was significantly delayed (403.0 +/- 230.9, 436.0 +/- 225.3 vs 152.3 +/- 124.7, P<0.01). Compared with those in group I, patients in groups II and III were associated with lower numerical rating scale pain scores (P<0.01) and less postoperative analgesic consumption (P<0.01). There was no significant difference in the variables mentioned above between groups II and III (P>0.05). CONCLUSION: Perineural dexamethasone has no additive/synergistic effect with subcostal TAP block on analgesic efficacy for the patients undergoing laparoscopic cholecystectomy.
学科主题	Gastroenterology & Hepatology
出版地	HANGZHOU
语种	英语
CSCD记录号	CSCD:5814011
WOS记录号	WOS:000385902900012
内容类型	期刊论文
源URL	[http://ir.lzu.edu.cn/handle/262010/188716]
专题	第二临床医学院_期刊论文
通讯作者	Wang, SK (reprint author), Lanzhou Univ, Hosp 2, Dept Orthoped, Lanzhou 730030, Peoples R China.
推荐引用方式 GB/T 7714	Huang, SH,Lu, J,Gan, HY,et al. Perineural dexamethasone does not enhance the analgesic efficacy of ultrasound-guided subcostal transversus abdominis plane block during laparoscopic cholecystectomy[J]. HEPATOBILIARY & PANCREATIC DISEASES INTERNATIONAL,2016,15(5):540-545.
APA	Huang, SH.,Lu, J.,Gan, HY.,Li, Y.,Peng, YG.,...&Wang, SK .(2016).Perineural dexamethasone does not enhance the analgesic efficacy of ultrasound-guided subcostal transversus abdominis plane block during laparoscopic cholecystectomy.HEPATOBILIARY & PANCREATIC DISEASES INTERNATIONAL,15(5),540-545.
MLA	Huang, SH,et al."Perineural dexamethasone does not enhance the analgesic efficacy of ultrasound-guided subcostal transversus abdominis plane block during laparoscopic cholecystectomy".HEPATOBILIARY & PANCREATIC DISEASES INTERNATIONAL 15.5(2016):540-545.