Epidemiology Characteristics, Methodological Assessment and Reporting of Statistical Analysis of Network Meta-Analyses in the Field of Cancer

doi:10.1038/srep37208

CORC > 兰州大学 > 兰州大学 > 第一临床医学院 > 期刊论文

	Epidemiology Characteristics, Methodological Assessment and Reporting of Statistical Analysis of Network Meta-Analyses in the Field of Cancer
	Ge, L; Tian, JH; Li, XX; Song, FJ; Li, L; Zhang, J; Li, G; Pei, GQ; Qiu, X; Yang, KH
刊名	SCIENTIFIC REPORTS
	2016-11-16
卷号	6
ISSN号	2045-2322
DOI	10.1038/srep37208
文献子类	Article
英文摘要	Because of the methodological complexity of network meta-analyses (NMAs), NMAs may be more vulnerable to methodological risks than conventional pair-wise meta-analysis. Our study aims to investigate epidemiology characteristics, conduction of literature search, methodological quality and reporting of statistical analysis process in the field of cancer based on PRISMA extension statement and modified AMSTAR checklist. We identified and included 102 NMAs in the field of cancer. 61 NMAs were conducted using a Bayesian framework. Of them, more than half of NMAs did not report assessment of convergence (60.66%). Inconsistency was assessed in 27.87% of NMAs. Assessment of heterogeneity in traditional meta-analyses was more common (42.62%) than in NMAs (6.56%). Most of NMAs did not report assessment of similarity (86.89%) and did not used GRADE tool to assess quality of evidence (95.08%). 43 NMAs were adjusted indirect comparisons, the methods used were described in 53.49% NMAs. Only 4.65% NMAs described the details of handling of multi group trials and 6.98% described the methods of similarity assessment. The median total AMSTAR-score was 8.00 (IQR: 6.00-8.25). Methodological quality and reporting of statistical analysis did not substantially differ by selected general characteristics. Overall, the quality of NMAs in the field of cancer was generally acceptable.
学科主题	Science & Technology - Other Topics
出版地	LONDON
语种	英语
WOS记录号	WOS:000387918900001
内容类型	期刊论文
源URL	[http://ir.lzu.edu.cn/handle/262010/188648]
专题	第一临床医学院_期刊论文
通讯作者	Yang, KH (reprint author), Lanzhou Univ, Evidence Based Med Ctr, Lanzhou 730000, Peoples R China.; Yang, KH (reprint author), Key Lab Evidence Based Med & Knowledge Translat G, Lanzhou 730000, Peoples R China.
推荐引用方式 GB/T 7714	Ge, L,Tian, JH,Li, XX,et al. Epidemiology Characteristics, Methodological Assessment and Reporting of Statistical Analysis of Network Meta-Analyses in the Field of Cancer[J]. SCIENTIFIC REPORTS,2016,6.
APA	Ge, L.,Tian, JH.,Li, XX.,Song, FJ.,Li, L.,...&Yang, KH .(2016).Epidemiology Characteristics, Methodological Assessment and Reporting of Statistical Analysis of Network Meta-Analyses in the Field of Cancer.SCIENTIFIC REPORTS,6.
MLA	Ge, L,et al."Epidemiology Characteristics, Methodological Assessment and Reporting of Statistical Analysis of Network Meta-Analyses in the Field of Cancer".SCIENTIFIC REPORTS 6(2016).