The pretreatment thrombocytosis may predict prognosis of patients with colorectal cancer: a systematic review and meta-analysis

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	The pretreatment thrombocytosis may predict prognosis of patients with colorectal cancer: a systematic review and meta-analysis
	Wang, YH; Deng, SJ; Yang, YD; Yao, N; Zhao, JM; Min, GT; Wang, J; Xu, TF; Zhao, PY; Wang, HP
刊名	BIOMARKERS IN MEDICINE
	2017-02
卷号	11 期号:2 页码:195-210
关键词	colorectal cancer meta-analysis platelet counts prognosis thrombocytosis
ISSN号	1752-0363
文献子类	Article
英文摘要	Aim: Recently, several studies have reported that thrombocytosis may be associated with the poor prognosis of colorectal cancer (CRC). Nevertheless, their conclusions were still controversial. Results & methodology: We searched PubMed, Embase, Cochrane Library and Web of Science up to April 2016. A total of 30 studies including 9129 patients were included in this meta-analysis. Thrombocytosis had a close relationship with the poor overall survival of CRC compared with normal platelet counts, with the pooled hazard ratios being 1.89 (95% CI: 1.45-2.47; p < 0.00001) and 1.83 (95% CI: 1.33-2.53; p = 0.0002), with univariate and multivariate analyses, respectively. Discussion & conclusion: This meta-analysis indicated that thrombocytosis may be a cost-effective and noninvasive indicator for poor prognosis of patients with CRC, especially for overall survival.
学科主题	Research & Experimental Medicine
出版地	LONDON
语种	英语
WOS记录号	WOS:000393680300011
内容类型	期刊论文
源URL	[http://ir.lzu.edu.cn/handle/262010/188639]
专题	第一临床医学院_期刊论文
通讯作者	Yang, YD (reprint author), First Peoples Hosp Xining City, Dept Gen Surg, Xining 810000, Qinghai Provinc, Peoples R China.; Yao, N (reprint author), Lanzhou Univ, Hosp 1, Dept Gen Surg, Lanzhou 730000, Gansu, Peoples R China.
推荐引用方式 GB/T 7714	Wang, YH,Deng, SJ,Yang, YD,et al. The pretreatment thrombocytosis may predict prognosis of patients with colorectal cancer: a systematic review and meta-analysis[J]. BIOMARKERS IN MEDICINE,2017,11(2):195-210.
APA	Wang, YH.,Deng, SJ.,Yang, YD.,Yao, N.,Zhao, JM.,...&Yao, N .(2017).The pretreatment thrombocytosis may predict prognosis of patients with colorectal cancer: a systematic review and meta-analysis.BIOMARKERS IN MEDICINE,11(2),195-210.
MLA	Wang, YH,et al."The pretreatment thrombocytosis may predict prognosis of patients with colorectal cancer: a systematic review and meta-analysis".BIOMARKERS IN MEDICINE 11.2(2017):195-210.