Euphorikanin A, a Diterpenoid Lactone with a Fused 5/6/7/3 Ring System from Euphorbia kansui

doi:10.1021/acs.orglett.6b01093

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	Euphorikanin A, a Diterpenoid Lactone with a Fused 5/6/7/3 Ring System from Euphorbia kansui
	Fei, DQ; Dong, LL; Qi, FM; Fan, GX; Li, HH; Li, ZY; Zhang, ZX; Zhang, ZX (reprint author), Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China.
刊名	ORGANIC LETTERS
	2016-06-17
卷号	18 期号:12 页码:2844-2847
ISSN号	1523-7060
DOI	10.1021/acs.orglett.6b01093
文献子类	Article
英文摘要	Euphorikanin A (1), an unprecedented diterpenoid lactone which possesses a novel 5/6/7/3-fused tetracyclic ring skeleton, was isolated from the roots of Euphorbia kansui. The chemical structure and absolute stereochemistry were elucidated on the basis of extensive spectroscopic methods and single-crystal X-ray diffraction analysis. Compound 1 exhibited moderate cytotoxicity against two human tumor cell lines HeLa and NCI-446. A proposed biosynthetic pathway of compound 1 is also described.
学科主题	Chemistry
出版地	WASHINGTON
资助项目	国家自然科学基金项目 ; 中央高校基本科研业务费专项资金
项目编号	National Natural Science Foundation of China [21402075, 21102065] ; Fundamental Research Funds for the Central Universities [lzujbky-2015-56, lzujbky-2015-58]
语种	英语
WOS记录号	WOS:000378303400014
资助机构	NSFC ; LZU
内容类型	期刊论文
源URL	[http://ir.lzu.edu.cn/handle/262010/179590]
专题	药学院_期刊论文
通讯作者	Fei, DQ; Zhang, ZX (reprint author), Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China.
推荐引用方式 GB/T 7714	Fei, DQ,Dong, LL,Qi, FM,et al. Euphorikanin A, a Diterpenoid Lactone with a Fused 5/6/7/3 Ring System from Euphorbia kansui[J]. ORGANIC LETTERS,2016,18(12):2844-2847.
APA	Fei, DQ.,Dong, LL.,Qi, FM.,Fan, GX.,Li, HH.,...&Zhang, ZX .(2016).Euphorikanin A, a Diterpenoid Lactone with a Fused 5/6/7/3 Ring System from Euphorbia kansui.ORGANIC LETTERS,18(12),2844-2847.
MLA	Fei, DQ,et al."Euphorikanin A, a Diterpenoid Lactone with a Fused 5/6/7/3 Ring System from Euphorbia kansui".ORGANIC LETTERS 18.12(2016):2844-2847.