Evaluation of the antimicrobial activity of 9-oxo-agerophorone against soil borne pathogens

doi:10.1007/s41348-016-0022-3

	Evaluation of the antimicrobial activity of 9-oxo-agerophorone against soil borne pathogens
	Liu, Xiaoman 1; Ouyang, Canbin 1; Li, Yuan 1; Yang, Dongsheng 2; Fang, Wensheng 1; Yan, Dongdong 1; Guo, Meixia 1; Cao, Aocheng 1; Wang, Qiuxia 1
刊名	JOURNAL OF PLANT DISEASES AND PROTECTION
	2016
卷号	123 期号:4 页码:163-170
关键词	9-Oxo-agerophorone Antifungal activity Antibacterial activity Scanning electron microscopy
ISSN号	1861-3829
DOI	10.1007/s41348-016-0022-3
通讯作者	Liu, Xiaoman
英文摘要	9-Oxo-agerophorone is a cadinene sesquiterpene, isolated from the leaves of Eupatorium adenophorum. This study evaluated the antimicrobial activity of 9-oxo-agerophorone against three strains of Ralstonia solanacearum and four pathogenic fungi, with an emphasis on the growth and morphogenesis of fungi at scanning electron microscopy level. The determination of minimal inhibitory concentrations demonstrated that 9-oxo-agerophorone exhibited moderate bactericidal activity against R. solanacearum strains. However, antifungal assays showed that 9-oxo-agerophorone has strong toxicity against Fusarium oxysporum, Bipolaris sorokiniana, Fusarium proliferatum, and Alternaria tenuissima with median lethal concentrations ranging from 0.476 to 0.357 mg ml(-1) after 4 days incubation on potato dextrose agar medium. The main changes observed by scanning electron microscopy after 9-oxo-agerophorone treatment were fungal cell wall shrinkage, loss of conidia, formation of short branches in F. oxysporum and F. proliferatum, collapse, broken cell walls, and increased hyphae diameter in A. tenuissima. The tested treatments were also effective in inhibiting spore germination of Fusarium species. The results indicated that 9-oxo-agerophorone is a potential candidate as a phytotherapeutic agent for soil-borne fungal diseases.
学科主题	Agriculture, Multidisciplinary ; Plant Sciences
语种	英语
出版者	SPRINGER HEIDELBERG
WOS记录号	WOS:000381801600003
内容类型	期刊论文
源URL	[http://111.203.20.206/handle/2HMLN22E/19676]
专题	农业环境与可持续发展研究所
作者单位	1.Chinese Acad Agr Sci, Inst Plant Protect, Beijing 100193, Peoples R China 2.Chinese Acad Agr Sci, Inst Environm & Sustainable Dev Agr, Beijing, Peoples R China
推荐引用方式 GB/T 7714	Liu, Xiaoman,Ouyang, Canbin,Li, Yuan,et al. Evaluation of the antimicrobial activity of 9-oxo-agerophorone against soil borne pathogens[J]. JOURNAL OF PLANT DISEASES AND PROTECTION,2016,123(4):163-170.
APA	Liu, Xiaoman.,Ouyang, Canbin.,Li, Yuan.,Yang, Dongsheng.,Fang, Wensheng.,...&Wang, Qiuxia.(2016).Evaluation of the antimicrobial activity of 9-oxo-agerophorone against soil borne pathogens.JOURNAL OF PLANT DISEASES AND PROTECTION,123(4),163-170.
MLA	Liu, Xiaoman,et al."Evaluation of the antimicrobial activity of 9-oxo-agerophorone against soil borne pathogens".JOURNAL OF PLANT DISEASES AND PROTECTION 123.4(2016):163-170.