Metagenomic analysis of the pinewood nematode microbiome reveals a symbiotic relationship critical for xenobiotics degradation

doi:10.1038/srep01869

CORC > 中国农业科学院 > 蔬菜花卉研究所

	Metagenomic analysis of the pinewood nematode microbiome reveals a symbiotic relationship critical for xenobiotics degradation
	Cheng, Xin-Yue 1; Tian, Xue-Liang 2,4; Wang, Yun-Sheng 2,5; Lin, Ren-Miao 2; Mao, Zhen-Chuan 2; Chen, Nansheng 3; Xie, Bing-Yan 2
刊名	SCIENTIFIC REPORTS
	2013
卷号	3 页码:-
ISSN号	2045-2322
DOI	10.1038/srep01869
通讯作者	Cheng, Xin-Yue
英文摘要	Our recent research revealed that pinewood nematode (PWN) possesses few genes encoding enzymes for degrading alpha-pinene, which is the main compound in pine resin. In this study, we examined the role of PWN microbiome in xenobiotics detoxification by metagenomic and bacteria culture analyses. Functional annotation of metagenomes illustrated that benzoate degradation and its related metabolisms may provide the main metabolic pathways for xenobiotics detoxification in the microbiome, which is obviously different from that in PWN that uses cytochrome P450 metabolism as the main pathway for detoxification. The metabolic pathway of degrading alpha-pinene is complete in microbiome, but incomplete in PWN genome. Experimental analysis demonstrated that most of tested cultivable bacteria can not only survive the stress of 0.4% alpha-pinene, but also utilize alpha-pinene as carbon source for their growth. Our results indicate that PWN and its microbiome have established a potentially mutualistic symbiotic relationship with complementary pathways in detoxification metabolism.
学科主题	Multidisciplinary Sciences ; MULTIDISCIPLINARY SCIENCES
语种	英语
出版者	NATURE PUBLISHING GROUP
WOS记录号	WOS:000319250600001
内容类型	期刊论文
源URL	[http://111.203.20.206/handle/2HMLN22E/101891]
专题	蔬菜花卉研究所
作者单位	1.Beijing Normal Univ, Coll Life Sci, Beijing 100875, Peoples R China 2.Chinese Acad Agr Sci, Inst Vegetables & Flowers, Beijing 100193, Peoples R China 3.Simon Fraser Univ, Dept Mol Biol & Biochem, Burnaby, BC V5A 1S6, Canada 4.Coll Henan Inst Sci & Technol, Xinxiang, Peoples R China 5.Hunan Agr Univ, Coll Plant Protect, Changsha, Hunan, Peoples R China
推荐引用方式 GB/T 7714	Cheng, Xin-Yue,Tian, Xue-Liang,Wang, Yun-Sheng,et al. Metagenomic analysis of the pinewood nematode microbiome reveals a symbiotic relationship critical for xenobiotics degradation[J]. SCIENTIFIC REPORTS,2013,3:-.
APA	Cheng, Xin-Yue.,Tian, Xue-Liang.,Wang, Yun-Sheng.,Lin, Ren-Miao.,Mao, Zhen-Chuan.,...&Xie, Bing-Yan.(2013).Metagenomic analysis of the pinewood nematode microbiome reveals a symbiotic relationship critical for xenobiotics degradation.SCIENTIFIC REPORTS,3,-.
MLA	Cheng, Xin-Yue,et al."Metagenomic analysis of the pinewood nematode microbiome reveals a symbiotic relationship critical for xenobiotics degradation".SCIENTIFIC REPORTS 3(2013):-.