| Bioactive Quinic Acid Derivatives from Ageratina adenophora | |
| Zhang, Mei1; Liu, Wan-Xue2; Zheng, Meng-Fei1,3; Xu, Qiao-Lin4; Wan, Fang-Hao2; Wang, Jing1,3; Lei, Ting1,3; Zhou, Zhong-Yu1; Tan, Jian-Wen1 | |
| 刊名 | MOLECULES
 |
| 2013 | |
| 卷号 | 18期号:11页码:14096-14104 |
| 关键词 | Ageratina adenophora qunic acid antimicrobial activity radical scavenging capacity DPPH |
| ISSN号 | 1420-3049 |
| DOI | 10.3390/molecules181114096 |
| 通讯作者 | Zhang, Mei |
| 英文摘要 | A novel quinic acid derivative, 5-O-trans-o-coumaroylquinic acid methyl ester (1), together with three known ones, chlorogenic acid methyl ester (2), macranthoin F (3) and macranthoin G (4), were isolated from the aerial parts of the invasive plant Ageratina adenophora (Spreng.). The structure of new compound 1 was elucidated on the basis of extensive spectroscopic analysis, including 1D- and 2D-NMR techniques. Compounds 2-4 were isolated from plant A. adenophora for the first time. All the compounds showed in vitro antibacterial activity toward five assayed bacterial strains, especially 3 and 4, which showed in vitro antibacterial activity against Salmonella enterica with MIC values of 7.4 and 14.7 mu M, respectively. Compound 1 was further found to display in vitro anti-fungal activity against spore germination of Magnaporthe grisea with an IC50 value 542.3 mu M. These four compounds were also tested for their antioxidant activity against DPPH (1,1-diphenyl-2-picrylhydrazyl) radical. |
| 学科主题 | Chemistry, Organic ; CHEMISTRY, ORGANIC |
| 语种 | 英语 |
| 出版者 | MDPI AG |
| WOS记录号 | WOS:000330311500064 |
| 内容类型 | 期刊论文 |
| 源URL | [http://111.203.20.206/handle/2HMLN22E/12079]  |
| 专题 | 植物保护研究所 |
| 作者单位 | 1.Chinese Acad Sci, Key Lab Plant Resources Conservat & Sustainable U, South China Bot Garden, Guangzhou 510650, Guangdong, Peoples R China 2.Chinese Acad Agr Sci, Inst Plant Protect, State Key Lab Biol Plant Dis & Insect Pests, Beijing 100193, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Guangdong Acad Forestry, Div Biotechnol, Guangzhou 510520, Guangdong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Mei,Liu, Wan-Xue,Zheng, Meng-Fei,et al. Bioactive Quinic Acid Derivatives from Ageratina adenophora[J]. MOLECULES,2013,18(11):14096-14104. |
| APA | Zhang, Mei.,Liu, Wan-Xue.,Zheng, Meng-Fei.,Xu, Qiao-Lin.,Wan, Fang-Hao.,...&Tan, Jian-Wen.(2013).Bioactive Quinic Acid Derivatives from Ageratina adenophora.MOLECULES,18(11),14096-14104. |
| MLA | Zhang, Mei,et al."Bioactive Quinic Acid Derivatives from Ageratina adenophora".MOLECULES 18.11(2013):14096-14104. |
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