Functional Analysis of the Ferric Uptake Regulator Gene fur in Xanthomonas vesicatoria

doi:10.1371/journal.pone.0149280

CORC > 中国农业科学院 > 植物保护研究所

	Functional Analysis of the Ferric Uptake Regulator Gene fur in Xanthomonas vesicatoria
	Liu, Huiqin 1,2,3; Dong, Chunling 2; Zhao, Tingchang 2; Han, Jucai 3; Wang, Tieling 2; Wen, Xiangzhen 4; Huang, Qi 5
刊名	PLOS ONE
	2016
卷号	11 期号:2 页码:-
ISSN号	1932-6203
DOI	10.1371/journal.pone.0149280
通讯作者	Liu, Huiqin
英文摘要	Iron is essential for the growth and survival of many organisms. Intracellular iron homeostasis must be maintained for cell survival and protection against iron toxicity. The ferric uptake regulator protein (Fur) regulates the high-affinity ferric uptake system in many bacteria. To investigate the function of the fur gene in Xanthomonas vesicatoria (Xv), we generated a fur mutant strain, fur-m, by site-directed mutagenesis. Whereas siderophore production increased in the Xv fur mutant, extracellular polysaccharide production, biofilm formation, swimming ability and quorum sensing signals were all significantly decreased. The fur mutant also had significantly reduced virulence in tomato leaves. The above-mentioned phenotypes significantly recovered when the Xv fur mutation allele was complemented with a wild-type fur gene. Thus, Fur either negatively or positively regulates multiple important physiological functions in Xv.
学科主题	Multidisciplinary Sciences
语种	英语
出版者	PUBLIC LIBRARY SCIENCE
WOS记录号	WOS:000371164700028
内容类型	期刊论文
源URL	[http://111.203.20.206/handle/2HMLN22E/11544]
专题	植物保护研究所
作者单位	1.Chinese Acad Agr Sci, Inst Plant Protect, State Key Lab Biol Plant Dis & Insect Pests, Beijing 100193, Peoples R China 2.Tianjin Agr Univ, Coll Hort & Landscape, Tianjin, Peoples R China 3.Shanxi Agr Univ, Agron Coll, Taigu, Shanxi, Peoples R China 4.Shanxi Agr Univ, Hort Coll, Taigu, Shanxi, Peoples R China 5.ARS, Floral & Nursery Plants Res Unit, USDA, Beltsville, MD USA
推荐引用方式 GB/T 7714	Liu, Huiqin,Dong, Chunling,Zhao, Tingchang,et al. Functional Analysis of the Ferric Uptake Regulator Gene fur in Xanthomonas vesicatoria[J]. PLOS ONE,2016,11(2):-.
APA	Liu, Huiqin.,Dong, Chunling.,Zhao, Tingchang.,Han, Jucai.,Wang, Tieling.,...&Huang, Qi.(2016).Functional Analysis of the Ferric Uptake Regulator Gene fur in Xanthomonas vesicatoria.PLOS ONE,11(2),-.
MLA	Liu, Huiqin,et al."Functional Analysis of the Ferric Uptake Regulator Gene fur in Xanthomonas vesicatoria".PLOS ONE 11.2(2016):-.