Association of functional nucleotide polymorphisms at DTH2 with the northward expansion of rice cultivation in Asia

doi:10.1073/pnas.1213962110

	Association of functional nucleotide polymorphisms at DTH2 with the northward expansion of rice cultivation in Asia
	Wu, Weixun 1; Zheng, Xiao-Ming 2; Lu, Guangwen 1; Zhong, Zhengzheng 2; Gao, He 1; Chen, Liping 1; Wu, Chuanyin 2; Wang, Hong-Jun 1; Wang, Qi 1; Zhou, Kunneng 1
刊名	PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
	2013
卷号	110 期号:8 页码:2775-2780
ISSN号	0027-8424
DOI	10.1073/pnas.1213962110
通讯作者	Wu, Weixun
英文摘要	Flowering time (i.e., heading date in crops) is an important ecological trait that determines growing seasons and regional adaptability of plants to specific natural environments. Rice (Oryza sativa L.) is a short-day plant that originated in the tropics. Increasing evidence suggests that the northward expansion of cultivated rice was accompanied by human selection of the heading date under noninductive long-day (LD) conditions. We report here the molecular cloning and characterization of DTH2 (for Days to heading on chromosome 2), a minor-effect quantitative trait locus that promotes heading under LD conditions. We show that DTH2 encodes a CONSTANS-like protein that promotes heading by inducing the florigen genes Heading date 3a and RICE FLOWERING LOCUS T 1, and it acts independently of the known floral integrators Heading date 1 and Early heading date 1. Moreover, association analysis and transgenic experiments identified two functional nucleotide polymorphisms in DTH2 that correlated with early heading and increased reproductive fitness under natural LD conditions in northern Asia. Our combined population genetics and network analyses suggest that DTH2 likely represents a target of human selection for adaptation to LD conditions during rice domestication and/or improvement, demonstrating an important role of minor-effect quantitative trait loci in crop adaptation and breeding.
学科主题	Multidisciplinary Sciences ; MULTIDISCIPLINARY SCIENCES
语种	英语
出版者	NATL ACAD SCIENCES
WOS记录号	WOS:000315954400042
内容类型	期刊论文
源URL	[http://111.203.20.206/handle/2HMLN22E/5066]
专题	作物科学研究所_转基因中心
作者单位	1.Nanjing Agr Univ, Jiangsu Plant Gene Engn Res Ctr, Natl Key Lab Crop Genet & Germplasm Enhancement, Nanjing 210095, Jiangsu, Peoples R China 2.Chinese Acad Agr Sci, Inst Crop Sci, Natl Key Facil Crop Gene Resources & Genet Improv, Beijing 100081, Peoples R China 3.Chinese Acad Sci, Inst Bot, State Key Lab Systemat & Evolutionary Bot, Beijing 100093, Peoples R China
推荐引用方式 GB/T 7714	Wu, Weixun,Zheng, Xiao-Ming,Lu, Guangwen,et al. Association of functional nucleotide polymorphisms at DTH2 with the northward expansion of rice cultivation in Asia[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,2013,110(8):2775-2780.
APA	Wu, Weixun.,Zheng, Xiao-Ming.,Lu, Guangwen.,Zhong, Zhengzheng.,Gao, He.,...&Wan, Jianmin.(2013).Association of functional nucleotide polymorphisms at DTH2 with the northward expansion of rice cultivation in Asia.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,110(8),2775-2780.
MLA	Wu, Weixun,et al."Association of functional nucleotide polymorphisms at DTH2 with the northward expansion of rice cultivation in Asia".PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 110.8(2013):2775-2780.