Antioxidant and immunoregulatory activity of alkali-extractable polysaccharides from mung bean

doi:10.1016/j.ijbiomac.2015.12.045

	Antioxidant and immunoregulatory activity of alkali-extractable polysaccharides from mung bean
	Yao, Yang 1; Zhu, Yingying 1,2; Ren, Guixing 1
刊名	INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
	2016
卷号	84 页码:289-294
关键词	Mung bean Alkali-extractable polysaccharide Antioxidant
ISSN号	0141-8130
DOI	10.1016/j.ijbiomac.2015.12.045
通讯作者	Yao, Yang
英文摘要	Alkali-extractable polysaccharides from the seeds of mung beans and two polysaccharide sub-fractions (MAP-1 and MAP-2) were isolated and purified by anion-exchange and gel filtration chromatography. The average molecular weights (Mws) of MAP-1 and MAP-2 were 94.2 kDa and 60.4 kDa, respectively. Monosaccharide component analysis indicated that MAP-1 was composed of Rha, Ara, Glu, Gal, and GalA in a molar ratio of 1.1:0.4:0.7:0.5:0.3. MAP-2 consisted of Xyl, Rha, Gal, Glu and GalA with a relative molar ratio of 0.4:1.4:1.6:0.5:0.2. Antioxidant assays indicated that both MAP-I and MAP-2 exhibit significant antioxidant activity in a dose-dependent manner. An in vitro study further showed that MAP-1 and MAP-2 were both able to stimulate the production of secretory molecules (NO, TNF-alpha and IL-6) by RAW 264.7 murine macrophages in a concentration-dependent manner. These findings suggest that the polysaccharides isolated in our study have immunoregulatory effects on macrophages and can be used as a beneficial health food. (C) 2015 Published by Elsevier B.V.
学科主题	Biochemistry & Molecular Biology ; Chemistry, Applied ; Polymer Science
语种	英语
出版者	ELSEVIER SCIENCE BV
WOS记录号	WOS:000369456800037
内容类型	期刊论文
源URL	[http://111.203.20.206/handle/2HMLN22E/4573]
专题	作物科学研究所_种质资源保存与研究中心
作者单位	1.Chinese Acad Agr Sci, Inst Crop Sci, 80 South Xueyuan Rd, Beijing 100081, Peoples R China 2.Univ Liege, Anim Sci Unit, Gembloux Agrobio Tech, Passage Deportes 2, B-5030 Gembloux, Belgium
推荐引用方式 GB/T 7714	Yao, Yang,Zhu, Yingying,Ren, Guixing. Antioxidant and immunoregulatory activity of alkali-extractable polysaccharides from mung bean[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2016,84:289-294.
APA	Yao, Yang,Zhu, Yingying,&Ren, Guixing.(2016).Antioxidant and immunoregulatory activity of alkali-extractable polysaccharides from mung bean.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,84,289-294.
MLA	Yao, Yang,et al."Antioxidant and immunoregulatory activity of alkali-extractable polysaccharides from mung bean".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 84(2016):289-294.