Genetic Properties of the Maize Nested Association Mapping Population

doi:10.1126/science.1174320

CORC > 中国农业科学院 > 作物科学研究所

	Genetic Properties of the Maize Nested Association Mapping Population
	McMullen, Michael D.1,2; Kresovich, Stephen 3; Villeda, Hector Sanchez 2; Bradbury, Peter 1,3; Li, Huihui 3,4,5; Sun, Qi 6; Flint-Garcia, Sherry 1,2; Thornsberry, Jeffry 7; Acharya, Charlotte 3; Bottoms, Christopher 2
刊名	SCIENCE
	2009
卷号	325 期号:5941 页码:737-740
ISSN号	0036-8075
DOI	10.1126/science.1174320
通讯作者	McMullen, Michael D.
英文摘要	Maize genetic diversity has been used to understand the molecular basis of phenotypic variation and to improve agricultural efficiency and sustainability. We crossed 25 diverse inbred maize lines to the B73 reference line, capturing a total of 136,000 recombination events. Variation for recombination frequencies was observed among families, influenced by local (cis) genetic variation. We identified evidence for numerous minor single-locus effects but little two-locus linkage disequilibrium or segregation distortion, which indicated a limited role for genes with large effects and epistatic interactions on fitness. We observed excess residual heterozygosity in pericentromeric regions, which suggested that selection in inbred lines has been less efficient in these regions because of reduced recombination frequency. This implies that pericentromeric regions may contribute disproportionally to heterosis.
学科主题	Multidisciplinary Sciences ; MULTIDISCIPLINARY SCIENCES
语种	英语
出版者	AMER ASSOC ADVANCEMENT SCIENCE
WOS记录号	WOS:000268723700046
内容类型	期刊论文
源URL	[http://111.203.20.206/handle/2HMLN22E/5500]
专题	作物科学研究所
作者单位	1.Univ Missouri, USDA ARS, Columbia, MO 65211 USA 2.Univ Missouri, Div Plant Sci, Columbia, MO 65211 USA 3.Cornell Univ, Inst Genom Divers, Ithaca, NY 14853 USA 4.Beijing Normal Univ, Sch Math Sci, Beijing 100875, Peoples R China 5.Chinese Acad Agr Sci, Inst Crop Sci, Beijing 100081, Peoples R China 6.Cornell Univ, Computat Biol Serv Unit, Ithaca, NY 14853 USA 7.NW Missouri State Univ, Maryville, MO 64468 USA 8.N Carolina State Univ, Dept Crop Sci, Raleigh, NC 27695 USA 9.Illumina Inc, San Diego, CA 92121 USA 10.Pioneer HiBred Int Inc, Johnston, IA 50131 USA
推荐引用方式 GB/T 7714	McMullen, Michael D.,Kresovich, Stephen,Villeda, Hector Sanchez,et al. Genetic Properties of the Maize Nested Association Mapping Population[J]. SCIENCE,2009,325(5941):737-740.
APA	McMullen, Michael D..,Kresovich, Stephen.,Villeda, Hector Sanchez.,Bradbury, Peter.,Li, Huihui.,...&Buckler, Edward S..(2009).Genetic Properties of the Maize Nested Association Mapping Population.SCIENCE,325(5941),737-740.
MLA	McMullen, Michael D.,et al."Genetic Properties of the Maize Nested Association Mapping Population".SCIENCE 325.5941(2009):737-740.