i-Motif Quadruplex DNA-Based Biosensor for Distinguishing Single- and Multiwalled Carbon Nanotubes

	i-Motif Quadruplex DNA-Based Biosensor for Distinguishing Single- and Multiwalled Carbon Nanotubes
	Peng YH ; Wang XH ; Xiao Y ; Feng LY ; Zhao C ; Ren JS ; Qu XG
刊名	journal of the american chemical society
	2009
卷号	131 期号:38 页码:13813-13818
关键词	ELECTROCHEMICAL DNA BLOOD-SERUM SURFACE SENSOR OLIGONUCLEOTIDES NANOPARTICLES SEQUENCE COMPLEX BINDING METAL
ISSN号	0002-7863
通讯作者	qu xg
中文摘要	the increasing worldwide demand for carbon nanotubes (cnts) and increasing concern regarding how to safely develop and use cnts are requiring a low-cost, simple, and highly sensitive cnt detection assay for toxicological evaluation and environmental monitoring. however, this goal is still far from being achieved. all the current cnt detection techniques are not,applicable for automation and field analysis because they are dependent on highly expensive special instruments and complicated sample preparation. on the basis of the capability of single-walled carbon nanotubes (swnts) to specifically induce human telomeric i-motif formation, we design an electrochemical dna (e-dna) sensor that can distinguish single- and multiwalled carbon nanotubes both in buffer and in cell extracts. the e-dna sensor can selectively detect swnts; with a direct detection limit of 0.2 ppm and has been demonstrated in cancer cell extracts. to the best of our knowledge, this is the first demonstration of a biosensing technique that can distinguish different types of nanotubes. our work will provide new insights into how to design a biosensor for detection of carbon nanotubes.
收录类别	ANGEW. CHEM. INT. ED., JACS, ADV. MATER., PRL, NUCLEIC ACIDS RES, NATURE SERIES (IF>10)
语种	英语
WOS记录号	WOS:000270186600052
公开日期	2010-06-18
内容类型	期刊论文
源URL	[http://202.98.16.49/handle/322003/12707]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Peng YH,Wang XH,Xiao Y,et al. i-Motif Quadruplex DNA-Based Biosensor for Distinguishing Single- and Multiwalled Carbon Nanotubes[J]. journal of the american chemical society,2009,131(38):13813-13818.
APA	Peng YH.,Wang XH.,Xiao Y.,Feng LY.,Zhao C.,...&Qu XG.(2009).i-Motif Quadruplex DNA-Based Biosensor for Distinguishing Single- and Multiwalled Carbon Nanotubes.journal of the american chemical society,131(38),13813-13818.
MLA	Peng YH,et al."i-Motif Quadruplex DNA-Based Biosensor for Distinguishing Single- and Multiwalled Carbon Nanotubes".journal of the american chemical society 131.38(2009):13813-13818.