Ochracenes A-I, Humulane-Derived Sesquiterpenoids from the Antarctic Fungus Aspergillus ochraceopetaliformis

CORC > 南海海洋研究所 > 中国科学院南海海洋研究所 > 中科院海洋生物资源可持续利用重点实验室

	Ochracenes A-I, Humulane-Derived Sesquiterpenoids from the Antarctic Fungus Aspergillus ochraceopetaliformis
	Wang, JF; He, WJ; Kong, FD; Tian, XP; Wang, P; Zhou, XJ; Liu, YH
刊名	JOURNAL OF NATURAL PRODUCTS
	2017
卷号	80 期号:6 页码:1725-1733
通讯作者	gale9888@163.com ; yonghongliu@scsio.ac.cn
中文摘要	Nine new humulane-derived sesquiterpenoids, ochracenes A-I (1-9), were isolated from the Antarctic fungus Aspergillus ochraceopetaliformis SCSIO 05702. Their structures including absolute configurations were elucidated on the basis of spectroscopic analysis, Mosher's method, and electronic circular dichroism analysis. Compared with previous humulane-type sesquiterpenoids, ochracenes A-I (1-9) featured novel carbon skeletons with corresponding methyl migration, ring cleavage, and carbon loss. Two unprecedented 8,9-secocyclic sesquiterpenoids (2 and 3) exhibited inhibitory effects on lipopolysaccharide-induced NO release in RAW 264.7 mouse macrophage cell lines with IC50 values of 14.6 +/- 0.5 and 18.3 +/- 1.7 mu M, respectively.
内容类型	期刊论文
源URL	[http://ir.scsio.ac.cn/handle/344004/16295]
专题	南海海洋研究所_中科院海洋生物资源可持续利用重点实验室
推荐引用方式 GB/T 7714	Wang, JF,He, WJ,Kong, FD,et al. Ochracenes A-I, Humulane-Derived Sesquiterpenoids from the Antarctic Fungus Aspergillus ochraceopetaliformis[J]. JOURNAL OF NATURAL PRODUCTS,2017,80(6):1725-1733.
APA	Wang, JF.,He, WJ.,Kong, FD.,Tian, XP.,Wang, P.,...&Liu, YH.(2017).Ochracenes A-I, Humulane-Derived Sesquiterpenoids from the Antarctic Fungus Aspergillus ochraceopetaliformis.JOURNAL OF NATURAL PRODUCTS,80(6),1725-1733.
MLA	Wang, JF,et al."Ochracenes A-I, Humulane-Derived Sesquiterpenoids from the Antarctic Fungus Aspergillus ochraceopetaliformis".JOURNAL OF NATURAL PRODUCTS 80.6(2017):1725-1733.