Antimicrobial Spirotetronate Metabolites from Marine-Derived Micromonospora harpali SCSIO GJ089

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	Antimicrobial Spirotetronate Metabolites from Marine-Derived Micromonospora harpali SCSIO GJ089
	Gui, C; Zhang, SW; Zhu, XC; Ding, WJ; Huang, HB; Gu, YC; Duan, YW; Ju, JH
刊名	JOURNAL OF NATURAL PRODUCTS
	2017
卷号	80 期号:5 页码:1594-1603
通讯作者	jju@scsio.ac.cn
中文摘要	Two new spirotetronate aglycones, 22-dehydroxymethyl-kijanolide (1) and 8-hydroxy-22-dehydroxymethyl-kijanolide (2), along with seven new spirotetronate glycosides, microsporanates A-F (3-8) and tetrocarcin P (9), together with three known tetrocarcins [tetrocarcins A (10), B (11), and AC6H (12)], were isolated from fermentation broths of the marine-derived Micromonospora harpali SCSIO GJ089. The structures of 1-9 were elucidated on the basis of 1D and 2D NMR and MS spectroscopic data. Compounds 3-8 feature an alpha,beta-unsaturated carbonyl moiety within their spirotetronate skeletons. Moreover, compounds 3-12 displayed strong to moderate antibacterial activities against Gram with MIC values ranging from 0.016 to 8.0 mu g/mL.
内容类型	期刊论文
源URL	[http://ir.scsio.ac.cn/handle/344004/16279]
专题	南海海洋研究所_中科院海洋生物资源可持续利用重点实验室
推荐引用方式 GB/T 7714	Gui, C,Zhang, SW,Zhu, XC,et al. Antimicrobial Spirotetronate Metabolites from Marine-Derived Micromonospora harpali SCSIO GJ089[J]. JOURNAL OF NATURAL PRODUCTS,2017,80(5):1594-1603.
APA	Gui, C.,Zhang, SW.,Zhu, XC.,Ding, WJ.,Huang, HB.,...&Ju, JH.(2017).Antimicrobial Spirotetronate Metabolites from Marine-Derived Micromonospora harpali SCSIO GJ089.JOURNAL OF NATURAL PRODUCTS,80(5),1594-1603.
MLA	Gui, C,et al."Antimicrobial Spirotetronate Metabolites from Marine-Derived Micromonospora harpali SCSIO GJ089".JOURNAL OF NATURAL PRODUCTS 80.5(2017):1594-1603.