ESI-FTICRMS Characterization of the Intermediates in Cycloisomerization of Trifluoromethyl-substituted Enynols through Changing the Protecting Group of Substrate

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	ESI-FTICRMS Characterization of the Intermediates in Cycloisomerization of Trifluoromethyl-substituted Enynols through Changing the Protecting Group of Substrate
	Qian R(钱荣) ; Guo YL(郭寅龙) ; Lv L(吕龙)
刊名	Chin. J. Chem.
	2009
卷号	27 期号:1 页码:123-129
ISSN号	1001-604X
其他题名	ESI-FTICRMS法研究含不同保护基的三氟甲基取代烯炔醇环异构化中间体
通讯作者	郭寅龙
英文摘要	A chemical method of changing the protecting group was coupled to MS, deuterium-labeled and NMR methods to characterize the intermediates in the palladium(II)-catalyzed cycloisomerization of trifluoromethyl-substituted enynols. It was demonstrated that the method of changing the protecting group of substrates not only caused a decrease in reaction speed, but also provided long-lived reaction intermediates detectable by conventional spectroscopic techniques. In this sense, two assumed reaction intermediates were intercepted and detected by electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry (ESI-FTICRMS). For further characterization of these intermediates, the gas-phase behavior of these intermediates was studied by sustained off-resonance irradiation collision-activated dissociation (SORI-CAD) experiments. On the basis of the detailed, spectral interpretation of the palladium-containing species, the fragmentation pathways of the intermediates have been proposed. The deuterium-labeled experiment helped confirm the nature of the intermediates.
学科主题	分析化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1002/cjoc.200990003
语种	英语
WOS记录号	WOS:000264039400021
公开日期	2013-02-25
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/19990]
专题	上海有机化学研究所_分析化学研究室
推荐引用方式 GB/T 7714	Qian R,Guo YL,Lv L. ESI-FTICRMS Characterization of the Intermediates in Cycloisomerization of Trifluoromethyl-substituted Enynols through Changing the Protecting Group of Substrate[J]. Chin. J. Chem.,2009,27(1):123-129.
APA	钱荣,郭寅龙,&吕龙.(2009).ESI-FTICRMS Characterization of the Intermediates in Cycloisomerization of Trifluoromethyl-substituted Enynols through Changing the Protecting Group of Substrate.Chin. J. Chem.,27(1),123-129.
MLA	钱荣,et al."ESI-FTICRMS Characterization of the Intermediates in Cycloisomerization of Trifluoromethyl-substituted Enynols through Changing the Protecting Group of Substrate".Chin. J. Chem. 27.1(2009):123-129.