金纳米粒子/聚多巴胺/碳纳米管修饰玻碳电极对核黄素的测定

CORC > 厦门大学 > 2016年第22卷

	金纳米粒子/聚多巴胺/碳纳米管修饰玻碳电极对核黄素的测定; Fabrication of Riboflavin Electrochemical Sensor Based on Au Nanoparticles/Polydopamine/Carbon Nanotubes Modified Glassy Carbon Electrode
	彭花萍 ; 余美玲 ; 刘馨 ; 刘盼 ; 陈伟 ; 刘爱林 ; 林新华 ; PENG Hua-ping ; YU Mei-ling ; LIU Xin ; LIU Pan ; CHEN Wei ; LIU Ai-lin ; LIN Xin-hua
刊名	http://electrochem.xmu.edu.cn/CN/abstract/abstract10185.shtml
	2016-02-29
关键词	核黄素金纳米粒子聚多巴胺多壁碳纳米管电化学 riboflavin gold nanoparticles polydopamine multi-walled carbon nanotubes electrochemistry
英文摘要	采用原位还原法制备金纳米粒子/聚多巴胺/碳纳米管（Au-PDA-MWNTs）复合材料，并将其用于建立高灵敏检测核黄素的电化学方法.采用紫外–可见光谱、扫描电镜、x-射线能谱对Au-PDA-MWNTs复合材料进行表征，采用循环伏安法和差示脉冲伏安法探讨核黄素（RF）在Au-PDA-MWNTs修饰的玻碳电极上的电化学行为，并对RF含量进行测定.该方法对核黄素的检测在5×10-9 mol·L-1～1×10-5 mol·L-1的范围内呈良好的线性关系（R=0.9906），检测限为1.7×10-9 mol·L-1.本方法操作简便、抗干扰能力强，方法可行，因此该方法成功实现了维生素药片中RF含量的测定.; A novel electrochemical platform for the high sensitivity detection of riboflavin was constructed by Au nanoparticles/polydopamine/carbon nanotubes (Au-PDA-MWCNTs) nanocomposite modified glassy carbon electrode. The Au-PDA-MWCNTs nanocomposite was synthesized by in situ reduction method. The characteristics of the as-prepared Au-PDA-MWCNTs nanocomposite modified electrodes were investigated by using UV-Vis spectroscopy, scanning electron microscopy (SEM) and electrochemical methods. Cyclic voltammetry (CV) and differential pulse voltammetry (DPV) were used to study the electrochemical behavior of riboflavin (RF) at Au-PDA-MWCNTs nanocomposite modified electrodes. The results demonstrated that the present electrochemical sensor exhibited a wide linear range from 5×10-9 mol•L-1to 1×10-5 mol•L-1 for detection of riboflavin, with a detection limit of 1.7×10-9 mol•L-1 (S/N = 3). The present method for high sensitivity determination of riboflavin by electrochemical method at Au-PDA-MWCNTs nanocomposite modified electrodes is simple, accurate, reliable and feasible with an excellent anti-interference ability against electroactive species and metal ions. Accordingly, the present method proved to be useful for the estimation of the RF content in pharmaceutical samples with satisfactory recovery.; 国家863计划资助项目（2012AA022604）；国家自然科学基金（21405015,21275028）；福建省自然科学基金资助项目（2014J05092）；福建省教育厅项目（JA13147）；大学生创新创业训练计划项目基金（201410392030）; 作者联系地址：1. 福建医科大学药学院药物分析系, 福建福州 350108; 2. 福建省高等学校纳米医药技术重点实验室，福建福州 350108; Author's Address: 1. Department of Pharmaceutical Analysis of the Fujian Medical University，Fuzhou 350004，China；2. The higher educational key laboratory for Nano Biomedical Technology of Fujian Province, Fujian Medical Univeristy，Fuzhou 350004，China; 通讯作者E-mail：xhl1963@sina.com
语种	中文
出版者	厦门大学《电化学》编辑部
内容类型	期刊论文
源URL	[http://dx.doi.org/10.13208/j.electrochem.150727]
专题	2016年第22卷
推荐引用方式 GB/T 7714	彭花萍,余美玲,刘馨,等. 金纳米粒子/聚多巴胺/碳纳米管修饰玻碳电极对核黄素的测定, Fabrication of Riboflavin Electrochemical Sensor Based on Au Nanoparticles/Polydopamine/Carbon Nanotubes Modified Glassy Carbon Electrode[J]. http://electrochem.xmu.edu.cn/CN/abstract/abstract10185.shtml,2016.
APA	彭花萍.,余美玲.,刘馨.,刘盼.,陈伟.,...&LIN Xin-hua.(2016).金纳米粒子/聚多巴胺/碳纳米管修饰玻碳电极对核黄素的测定.http://electrochem.xmu.edu.cn/CN/abstract/abstract10185.shtml.
MLA	彭花萍,et al."金纳米粒子/聚多巴胺/碳纳米管修饰玻碳电极对核黄素的测定".http://electrochem.xmu.edu.cn/CN/abstract/abstract10185.shtml (2016).