柠檬酸修饰(CA/GC)电极对多巴胺(DA)和肾上腺素(EP)同时检测

CORC > 厦门大学 > 2011年第17卷

	柠檬酸修饰(CA/GC)电极对多巴胺(DA)和肾上腺素(EP)同时检测; Simultaneous Determination of Dopamine(DA)and Epinephrine (EP) at CA/GC Electrode
	任旺 ; 张英 ; 李敏娇 ; REN Wang ; ZHANG Ying ; LI Min-Jiao
刊名	http://electrochem.xmu.edu.cn/CN/abstract/abstract9805.shtml
	2011-08-28
关键词	修饰电极柠檬酸多巴胺肾上腺素 modified electrode citric acid dopamine epinephrine
英文摘要	应用电沉积方法制备柠檬酸修饰电极(CA/GC), 差分脉冲法研究多巴胺(DA)和肾上腺素(EP)在该修饰电极上的电化学行为．结果表明, 两样品DA、EP在该电极的还原峰电位差380 mV, 而抗坏血酸(AA)在此电位区无还原峰, 因此可实现该修饰电极对DA和EP的同时检测, 而且高浓度AA不发生干扰．在pH 6.0的磷酸盐缓冲液中, DA和EP还原峰电流与其浓度分别在1.0×10-6 ~ 6.0×10-5 mol•L-1和2.0×10-6 ~ 6.0×10-5 mol•L-1 范围内呈线性关系．CA/GC电极制备简单, 重现性好, 可望用于多巴胺针剂(DA)和肾上腺素针剂(EP)的同时检测; The citric acid modified glassy carbon electrode (CA/GC) was prepared by potentiostatic technique and was used for detections of dopamine (DA), epinephrine (EP), and their mixtures by differential pulse voltammetry (DPV). The modified electrode shows the enhanced sensitivity and excellent electrochemical discrimination to DA and EP. The cathodic potential difference between DA and EP was about 380 mV, while no cathodic reduction of ascorbic acid (AA) was observed because the oxidation of AA is an irreversible reaction at the sensor. As a result, DA and EP could be determined simultaneously with the interferences of high concentrations of AA being eliminated. The reduction peak currents obtained in the phosphate buffer solutions at pH=6.0 were linearly dependent on the DA and EP concentrations in the ranges of 1.0×10-6～6.0×10-5 mol?L-1 and 2.0×10-6～6.0×10-5 mol?L-1, respectively. The proposed method showed potential applications in the simultaneous detections of DA and EP in injections.; 四川省教育厅基金项目(10ZB102) , 四川理工学院科技项目(2009xjky1001) 资助; 作者联系地址：四川理工学院化学与制药工程学院, 四川, 自贡 643000; Author's Address: College of Chemical & Pharmaceutical Engineering, Sichuan University of Science & Engineering, Zigong 643000, Sichuan, China; 通讯作者E-mail：renwangzhy@163.com
语种	中文
出版者	厦门大学《电化学》编辑部
内容类型	期刊论文
源URL	[http://dspace.xmu.edu.cn/handle/2288/58433]
专题	2011年第17卷
推荐引用方式 GB/T 7714	任旺,张英,李敏娇,等. 柠檬酸修饰(CA/GC)电极对多巴胺(DA)和肾上腺素(EP)同时检测, Simultaneous Determination of Dopamine(DA)and Epinephrine (EP) at CA/GC Electrode[J]. http://electrochem.xmu.edu.cn/CN/abstract/abstract9805.shtml,2011.
APA	任旺,张英,李敏娇,REN Wang,ZHANG Ying,&LI Min-Jiao.(2011).柠檬酸修饰(CA/GC)电极对多巴胺(DA)和肾上腺素(EP)同时检测.http://electrochem.xmu.edu.cn/CN/abstract/abstract9805.shtml.
MLA	任旺,et al."柠檬酸修饰(CA/GC)电极对多巴胺(DA)和肾上腺素(EP)同时检测".http://electrochem.xmu.edu.cn/CN/abstract/abstract9805.shtml (2011).