New A-nor steroids and their antifouling activity from the Chinese marine sponge Acanthella cavernosa

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	New A-nor steroids and their antifouling activity from the Chinese marine sponge Acanthella cavernosa
	Qiu, Yan ; Deng, Zhi Wei ; Xu, Minjuan ; Li, Qingshan ; Lin, Wen Han ; Qiu Y(邱彦)
刊名	http://dx.doi.org/10.1016/j.steroids.2008.08.006
	2008-12-22
关键词	KALIHINOL LARVAE
英文摘要	National Hi-Tech Development Project (863 project) [2006AA09Z446, 2006DFA31100, 2006AA09Z405]; NSFC [30672607, 30600053, 40176038, 30171106]; International Cooperation Projects of BMBF-MOST; A chemical examination of the Chinese sponge Acanthella cavernosa resulted in the isolation of three new A-ring contracted steroids, the ethyl esters of 2 beta-hydroxy-4,7-diketoA-norcholest-5-en-2-oic acid (1), 24S-ethyl-2 beta-hydroxy- 4,7-diketo-A-norcholest-5-en-2-oic acid (2), and 2 beta-hydroxy-4,7-diketo-24R-methyl-A-norcholest-5,22(E)-dien-2-oic acid (3), along with four other known steroids (4-7). The structures were determined on the basis of extensive spectroscopic analysis. Compounds 1-3 showed antifouling activity toward the settlement inhibition of Balanus albicostatus with the EC(50) values of 8.2, 215, 31.6 mu g/mL, respectively. (C) 2008 Elsevier Inc. All rights reserved.
语种	英语
出版者	STEROIDS
内容类型	期刊论文
源URL	[http://dspace.xmu.edu.cn/handle/2288/93367]
专题	医学院－已发表论文
推荐引用方式 GB/T 7714	Qiu, Yan,Deng, Zhi Wei,Xu, Minjuan,et al. New A-nor steroids and their antifouling activity from the Chinese marine sponge Acanthella cavernosa[J]. http://dx.doi.org/10.1016/j.steroids.2008.08.006,2008.
APA	Qiu, Yan,Deng, Zhi Wei,Xu, Minjuan,Li, Qingshan,Lin, Wen Han,&邱彦.(2008).New A-nor steroids and their antifouling activity from the Chinese marine sponge Acanthella cavernosa.http://dx.doi.org/10.1016/j.steroids.2008.08.006.
MLA	Qiu, Yan,et al."New A-nor steroids and their antifouling activity from the Chinese marine sponge Acanthella cavernosa".http://dx.doi.org/10.1016/j.steroids.2008.08.006 (2008).