Significance of CD4 T-Cell Adenosine Triphosphate Levels Monitoring in Elderly Renal Transplant Recipients

CORC > 厦门大学 > 医学院－已发表论文

	Significance of CD4 T-Cell Adenosine Triphosphate Levels Monitoring in Elderly Renal Transplant Recipients
	Wu, Z. ; Zhou, H. ; Yang, S. ; Cai, J. ; Wang, Q. ; Liao, L. ; Tan, J. ; Wu Z(吴振) ; Zhou H(周虎) ; Wang Q(王骞)
刊名	http://dx.doi.org/10.1016/j.transproceed.2012.05.083
	2012-12
关键词	KIDNEY-TRANSPLANTATION IMMUKNOW ASSAY
英文摘要	Major Research Project Fund [2009Y4001]; Technology Innovation Platform Project Fund of Fujian Province [2008J1006]; Fujian Provincial Natural Science Foundation of China [2012J01408, 2011J01239]; Objectives. To find the significance of CD4 T-cell adenosine triphosphate (ATP) levels in elderly renal recipients in correlation with drug doses, levels, and clinical parameters. Methods. Drug doses and levels, CD4 T-cell ATP levesl (162 sequential samples), and other clinical data were collected and assessed among 31 elderly renal recipients who underwent transplantations from November 2007 to March 2011. Results. Among subjects with stable clinical status, the main ATP levels pretransplantation were not significantly different from those posttransplantation: 302.4 +/- 97.5 ng/mL versus 288.8 +/- 102.6 ng/mL (P > .05). There was no relationship between ATP levels and tacrolimus concentrations or doses. In 12 patients experiencing infection, the ATP levels were significantly lower then those of subjects showing a stable clinical status: 127.3 +/- 92.8 versus 288.8 +/- 102.6 ng/mL (P < .01). Six patients with biopsy-proven acute rejection episodes did not show significantly higher ATP levels compared with those who were clinically stable: 26.2 +/- 224.8 versus 288.8 +/- 102.6 (P > .05). Conclusions. CD4 T-cell ATP levels were valuable to monitor immunosuppression among elderly renal transplant recipients.
语种	英语
出版者	TRANSPL P
内容类型	期刊论文
源URL	[http://dspace.xmu.edu.cn/handle/2288/93365]
专题	医学院－已发表论文
推荐引用方式 GB/T 7714	Wu, Z.,Zhou, H.,Yang, S.,et al. Significance of CD4 T-Cell Adenosine Triphosphate Levels Monitoring in Elderly Renal Transplant Recipients[J]. http://dx.doi.org/10.1016/j.transproceed.2012.05.083,2012.
APA	Wu, Z..,Zhou, H..,Yang, S..,Cai, J..,Wang, Q..,...&王骞.(2012).Significance of CD4 T-Cell Adenosine Triphosphate Levels Monitoring in Elderly Renal Transplant Recipients.http://dx.doi.org/10.1016/j.transproceed.2012.05.083.
MLA	Wu, Z.,et al."Significance of CD4 T-Cell Adenosine Triphosphate Levels Monitoring in Elderly Renal Transplant Recipients".http://dx.doi.org/10.1016/j.transproceed.2012.05.083 (2012).