Approaches for Recognizing Disease Genes Based on Network

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	Approaches for Recognizing Disease Genes Based on Network
	Zou, Quan ; Li, Jinjin ; Wang, Chunyu ; Zeng, Xiangxiang ; Zou Q(邹权) ; Ceng XX(曾湘祥)
刊名	http://dx.doi.org/10.1155/2014/416323
	2014
关键词	ONLINE MENDELIAN INHERITANCE CANDIDATE GENES MAN OMIM HETEROGENEOUS NETWORK HUMAN PHENOME DISORDERS PRIORITIZATION IDENTIFICATION KNOWLEDGEBASE INTERACTOME
英文摘要	Natural Science Foundation of China [61370010, 61202011, 61271346, 61172098, 60932008]; Ph.D. Programs Foundation of Ministry of Education of China [20120121120039]; Diseases are closely related to genes, thus indicating that genetic abnormalities may lead to certain diseases. The recognition of disease genes has long been a goal in biology, which may contribute to the improvement of health care and understanding gene functions, pathways, and interactions. However, few large-scale gene-gene association datasets, disease-disease association datasets, and gene-disease association datasets are available. A number of machine learning methods have been used to recognize disease genes based on networks. This paper states the relationship between disease and gene, summarizes the approaches used to recognize disease genes based on network, analyzes the core problems and challenges of the methods, and outlooks future research direction.
语种	英语
出版者	HINDAWI PUBLISHING CORPORATION
内容类型	期刊论文
源URL	[http://dspace.xmu.edu.cn/handle/2288/92761]
专题	信息技术－已发表论文
推荐引用方式 GB/T 7714	Zou, Quan,Li, Jinjin,Wang, Chunyu,et al. Approaches for Recognizing Disease Genes Based on Network[J]. http://dx.doi.org/10.1155/2014/416323,2014.
APA	Zou, Quan,Li, Jinjin,Wang, Chunyu,Zeng, Xiangxiang,邹权,&曾湘祥.(2014).Approaches for Recognizing Disease Genes Based on Network.http://dx.doi.org/10.1155/2014/416323.
MLA	Zou, Quan,et al."Approaches for Recognizing Disease Genes Based on Network".http://dx.doi.org/10.1155/2014/416323 (2014).