Biological functions of microRNAs: a review

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	Biological functions of microRNAs: a review
	Huang, Yong ; Shen, Xing Jia ; Zou, Quan ; Wang, Sheng Peng ; Tang, Shun Ming ; Zhang, Guo Zheng ; Zou Q(邹权)
刊名	http://dx.doi.org/10.1007/s13105-010-0050-6
	2011-03
关键词	GENE-EXPRESSION CELL-DIFFERENTIATION NEURONAL DIFFERENTIATION CAENORHABDITIS-ELEGANS INFLAMMATORY RESPONSE VASCULAR INTEGRITY MESSENGER-RNAS CANCER CELLS STEM-CELLS C-ELEGANS
英文摘要	National Basic Research 973 Program [2005CB121004]; National High Tech Development Project of China; 863 Program [2006AA10A119]; Innovation Foundation for Graduate Students of Jiangsu Province; Natural Science Foundation of China [61001013]; MicroRNAs (miRNAs) are a recently discovered family of endogenous, noncoding RNA molecules approximately 22 nt in length. miRNAs modulate gene expression post-transcriptionally by binding to complementary sequences in the coding or 3' untranslated region of target messenger RNAs (mRNAs). It is now clear that the biogenesis and function of miRNAs are related to the molecular mechanisms of various clinical diseases, and that they can potentially regulate every aspect of cellular activity, including differentiation and development, metabolism, proliferation, apoptotic cell death, viral infection and tumorgenesis. Here, we review recent advances in miRNA research, and discuss the diverse roles of miRNAs in disease.
语种	英语
出版者	J PHYSIOL BIOCHEM
内容类型	期刊论文
源URL	[http://dspace.xmu.edu.cn/handle/2288/92449]
专题	信息技术－已发表论文
推荐引用方式 GB/T 7714	Huang, Yong,Shen, Xing Jia,Zou, Quan,et al. Biological functions of microRNAs: a review[J]. http://dx.doi.org/10.1007/s13105-010-0050-6,2011.
APA	Huang, Yong.,Shen, Xing Jia.,Zou, Quan.,Wang, Sheng Peng.,Tang, Shun Ming.,...&邹权.(2011).Biological functions of microRNAs: a review.http://dx.doi.org/10.1007/s13105-010-0050-6.
MLA	Huang, Yong,et al."Biological functions of microRNAs: a review".http://dx.doi.org/10.1007/s13105-010-0050-6 (2011).