Comparison of the shape parameters of DNA-cationic lipid complexes and model polyelectrolyte-lipid complexes

	Comparison of the shape parameters of DNA-cationic lipid complexes and model polyelectrolyte-lipid complexes
	Sun, Y ; Yu, XJ ; Takaoka, Y ; Oh-I, SI ; Duzgunes, N ; Hirota, S
刊名	journal of colloid and interface science
	2004-08-15
卷号	276 期号:2 页码:317-322
关键词	shape parameter DNA rheological behavior lipoplexes viscosity polyanion solutions
产权排序	1;1
英文摘要	in this study, we used a rheological method to study the shape of dna-cationic lipid complexes and model polyelectrolyte-lipid complexes. we introduced two kinds of anionic polyelectrolytes, sodium polygalacturonate (pgu) and sodium dextran sulfate (dss), of varying size, as models for dna. the prepared complexes were incubated under laminar flow conditions. the results show the same quantitative relation between the shape parameter of lipoplexes and the length of anionic polyelectrolytes, including dna. the rheological behavior of pgu and dss were similar to that of dna. (c) 2004 elsevier inc. all rights reserved.
WOS标题词	science & technology ; physical sciences
类目[WOS]	chemistry, physical
研究领域[WOS]	chemistry
关键词[WOS]	gene-transfer ; liposome complexes ; transfection ; lipoplexes ; morphology ; expression ; delivery ; cells
收录类别	SCI
原文出处	true
语种	英语
WOS记录号	WOS:000223006200008
公开日期	2010-11-30
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/81925]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China 2.Univ Pacific, Sch Dent, Dept Microbiol, San Francisco, CA 94115 USA 3.Tokyo Denki Univ, Chigasaki, Kanagawa 2530054, Japan
推荐引用方式 GB/T 7714	Sun, Y,Yu, XJ,Takaoka, Y,et al. Comparison of the shape parameters of DNA-cationic lipid complexes and model polyelectrolyte-lipid complexes[J]. journal of colloid and interface science,2004,276(2):317-322.
APA	Sun, Y,Yu, XJ,Takaoka, Y,Oh-I, SI,Duzgunes, N,&Hirota, S.(2004).Comparison of the shape parameters of DNA-cationic lipid complexes and model polyelectrolyte-lipid complexes.journal of colloid and interface science,276(2),317-322.
MLA	Sun, Y,et al."Comparison of the shape parameters of DNA-cationic lipid complexes and model polyelectrolyte-lipid complexes".journal of colloid and interface science 276.2(2004):317-322.