DNA Mismatch Recognition by a Hexacoordinate Silicon Sandwich-Ruthenium Hybrid Complex

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	DNA Mismatch Recognition by a Hexacoordinate Silicon Sandwich-Ruthenium Hybrid Complex
	Fu, Chen ; Harms, Klaus ; Zhang, Lilu ; Meggers, Eric ; ERIC MEGGERS
刊名	http://dx.doi.org/10.1021/om500367a
	2014-06-23
关键词	RHODIUM INTERCALATOR HALOSILANE ADDUCTS METAL-COMPLEXES STEREOCHEMISTRY ENTEROBACTIN CHEMISTRY REACTIVITY
英文摘要	LOEWE research cluster (SynChemBio) of the Federal State of Hessen, Germany; The diastereoselective synthesis of two dinuclear Ru-Si complexes is reported, in which silicon(IV) is coordinated in an octahedral fashion by two 1,10-phenanthrolines and one 4,5-pyrenediolato ligand and additionally eta(6)-coordinated to a (eta 5-pentamethylcyclopentadienyl)ruthenium(II) moiety through one fused benzene ring of the pyrene ligand. One of these Ru-Si hybrid complexes was found to selectively stabilize DNA duplexes that contain cytosine-cytosine or cytosine thymine mismatches, and it is proposed that this occurs by a novel dual insertion/intercalation binding mode in which the entire ruthenium sandwich unit is introduced into the DNA pi-stacking at the site of the DNA mismatch.
语种	英语
出版者	AMER CHEMICAL SOC
内容类型	期刊论文
源URL	[http://dspace.xmu.edu.cn/handle/2288/89268]
专题	化学化工－已发表论文
推荐引用方式 GB/T 7714	Fu, Chen,Harms, Klaus,Zhang, Lilu,et al. DNA Mismatch Recognition by a Hexacoordinate Silicon Sandwich-Ruthenium Hybrid Complex[J]. http://dx.doi.org/10.1021/om500367a,2014.
APA	Fu, Chen,Harms, Klaus,Zhang, Lilu,Meggers, Eric,&ERIC MEGGERS.(2014).DNA Mismatch Recognition by a Hexacoordinate Silicon Sandwich-Ruthenium Hybrid Complex.http://dx.doi.org/10.1021/om500367a.
MLA	Fu, Chen,et al."DNA Mismatch Recognition by a Hexacoordinate Silicon Sandwich-Ruthenium Hybrid Complex".http://dx.doi.org/10.1021/om500367a (2014).