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One pot conjugation of the polypeptides directed by phosphorus oxychloride
Zhou, N. ; Liu, Y. ; Zhou, G. J. ; Zhao, Y. F. ; Liu Y(刘艳)
刊名http://dx.doi.org/10.1111/j.1399-3011.2005.00231.x
2005-04
关键词PEPTIDE LIBRARIES
英文摘要A series of homopeptides and their conjugates were synthesized in one pot reaction in the presence of phosphorus oxychloride and the conjugate yield was structurally dependent. Menthol and benzylamine conjugated to the homopeptides quantitatively. Homopeptides when treated with diisopropyloxyphosphite (DIPPH) and NaClO yield the corresponding N-phosphoryl peptides. Electrospray ionization-mass spectrometry (ESI-MS)/MS was used to study the structure of peptide conjugates. This paper reports a simple method to synthesize the homopeptides and their conjugate derivatives and the fact that phosphoryl peptides could also be obtained by one pot reaction.
语种英语
内容类型期刊论文
源URL[http://dspace.xmu.edu.cn/handle/2288/61331]  
专题化学化工-已发表论文
推荐引用方式
GB/T 7714
Zhou, N.,Liu, Y.,Zhou, G. J.,et al. One pot conjugation of the polypeptides directed by phosphorus oxychloride[J]. http://dx.doi.org/10.1111/j.1399-3011.2005.00231.x,2005.
APA Zhou, N.,Liu, Y.,Zhou, G. J.,Zhao, Y. F.,&刘艳.(2005).One pot conjugation of the polypeptides directed by phosphorus oxychloride.http://dx.doi.org/10.1111/j.1399-3011.2005.00231.x.
MLA Zhou, N.,et al."One pot conjugation of the polypeptides directed by phosphorus oxychloride".http://dx.doi.org/10.1111/j.1399-3011.2005.00231.x (2005).
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