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A concise and fully selective synthesis of the ant venom alkaloid (3S,5R,8S,9S)-3-butyl-5-propyl-8-hydroxyindolizidine
Lin, Geng-Jie ; Huang, Pei-Qiang ; Huang PQ(黄培强)
2009
英文摘要A seven-step synthesis of (3S,5R,8S,9S)-3-butyl-5-propyl-8-hydroxyindolizidine (2), an ant venom alkaloid isolated from Myrmicaria melanogaster, is disclosed with an overall yield of 28.9%. The key feature of the synthesis is the use of the iodocyclization for the introduction of the hydroxyl group of the 3-piperidinol. Remarkably, all the reaction steps proceeded with excellent chemo-, regio- and/or diastereoselectivities.; NSF of China [20832005]; National Basic Research Program (973 Program) of China [2010CB833206]
语种英语
出版者ROYAL SOC CHEMISTRY
内容类型期刊论文
源URL[http://dx.doi.org/doi:10.1039/B912190K]  
专题化学化工-已发表论文
推荐引用方式
GB/T 7714
Lin, Geng-Jie,Huang, Pei-Qiang,Huang PQ. A concise and fully selective synthesis of the ant venom alkaloid (3S,5R,8S,9S)-3-butyl-5-propyl-8-hydroxyindolizidine[J],2009.
APA Lin, Geng-Jie,Huang, Pei-Qiang,&黄培强.(2009).A concise and fully selective synthesis of the ant venom alkaloid (3S,5R,8S,9S)-3-butyl-5-propyl-8-hydroxyindolizidine..
MLA Lin, Geng-Jie,et al."A concise and fully selective synthesis of the ant venom alkaloid (3S,5R,8S,9S)-3-butyl-5-propyl-8-hydroxyindolizidine".(2009).
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