Bioglass/chitosan-polycaprolactone bilayered composite scaffolds intended for osteochondral tissue engineering

CORC > 厦门大学 > 材料学院－已发表论文

	Bioglass/chitosan-polycaprolactone bilayered composite scaffolds intended for osteochondral tissue engineering
	Yao, Qingqing ; Nooeaid, Patcharakamon ; Detsch, Rainer ; Roether, Judith A. ; Dong, Yanming ; Goudouri, Ourania-Menti ; Schubert, Dirk W. ; Boccaccini, Aldo R. ; Dong YM(董炎明)
刊名	http://dx.doi.org/10.1002/jbm.a.35125
	2014
关键词	Biodegradation Biomechanics Chitin Chitosan Foams Fourier transform infrared spectroscopy Mechanical properties Plastic coatings Polycaprolactone Polymers Scanning electron microscopy Tissue Tissue engineering X ray diffraction
英文摘要	Polymer-coated 45S5 Bioglass? (BG)/chitosan-polycaprolactone (BG/CS-PCL) bilayered composite scaffolds were prepared via foam replication and freeze-drying techniques for application in osteochondral tissue engineering. The CSPCL coated and uncoated BG scaffolds were characterized by X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy and scanning electron microscopy (SEM). The mechanical properties of the coated scaffolds were significantly improved in comparison to uncoated scaffolds. The bioactivity and biodegradation behavior of scaffolds were studied in simulated body fluid (SBF) for up to 28 days. The interface between the BG scaffold and the polymer coating layer was observed by SEM and a suitable interpenetration of the polymer into the scaffold struts was found. The effects of coated and uncoated BG scaffolds on MG-63 osteoblastlike cells were evaluated by cell viability, adhesion and proliferation.
语种	英语
出版者	John Wiley and Sons Inc.
内容类型	期刊论文
源URL	[http://dspace.xmu.edu.cn/handle/2288/87439]
专题	材料学院－已发表论文
推荐引用方式 GB/T 7714	Yao, Qingqing,Nooeaid, Patcharakamon,Detsch, Rainer,et al. Bioglass/chitosan-polycaprolactone bilayered composite scaffolds intended for osteochondral tissue engineering[J]. http://dx.doi.org/10.1002/jbm.a.35125,2014.
APA	Yao, Qingqing.,Nooeaid, Patcharakamon.,Detsch, Rainer.,Roether, Judith A..,Dong, Yanming.,...&董炎明.(2014).Bioglass/chitosan-polycaprolactone bilayered composite scaffolds intended for osteochondral tissue engineering.http://dx.doi.org/10.1002/jbm.a.35125.
MLA	Yao, Qingqing,et al."Bioglass/chitosan-polycaprolactone bilayered composite scaffolds intended for osteochondral tissue engineering".http://dx.doi.org/10.1002/jbm.a.35125 (2014).