CORC  > 厦门大学  > 材料学院-已发表论文
UV-curable pressure sensitive adhesive films: effects of biocompatible plasticizers on mechanical and adhesion properties
Dana, Sara Faraji ; Duc-Viet Nguyen ; Kochhar, Jaspreet Singh ; Liu, Xiang-Yang ; Kang, Lifeng ; Liu XY(刘向阳)
刊名http://dx.doi.org/10.1039/c3sm50879j
2013
关键词TRANSDERMAL DRUG-DELIVERY POLY(ETHYLENE GLYCOL) CROSS-LINKING HYDROGELS SYSTEMS BLENDS STRENGTH PATCHES PHOTOLITHOGRAPHY PERMEABILITY
英文摘要SINGA scholarship; National University of Singapore; Singapore National Medical Research Council (NMRC) [NIG09May 029]; We developed a new approach to fabricate pressure sensitive adhesive (PSA) hydrogel films for dermatological applications. These hydrogel films were fabricated using polyvinylpyrrolidone (PVP), poly(ethylene glycol) diacrylate (PEGDA) and polyethylene glycol (PEG) with/without propylene glycol (PG) via photo-polymerization. Hydrogel films with a thickness ranging from 130 to 1190 mu m were obtained. The surface morphology and drug distribution within the films were found to be uniform. The effects of different factors (polymeric composition, i.e., PEG/PG presence and film thickness) on the functional properties (i.e., rheological and mechanical properties, adhesion performance and drug distribution) of the films were investigated. The addition of plasticizers, namely PEG and PG, resulted in a simultaneous increase in elasticity and adhesiveness of these hydrogels, via the formation of hydrogen bonds, which has a direct correlation with their adhesion properties. The new approach is potentially useful for industrial applications, due to the simple procedure, precise control over film thickness, minimal usage of solvents and adjustable mechanical, rheological and adhesive properties.
语种英语
出版者ROYAL SOC CHEMISTRY
内容类型期刊论文
源URL[http://dspace.xmu.edu.cn/handle/2288/87217]  
专题材料学院-已发表论文
推荐引用方式
GB/T 7714
Dana, Sara Faraji,Duc-Viet Nguyen,Kochhar, Jaspreet Singh,et al. UV-curable pressure sensitive adhesive films: effects of biocompatible plasticizers on mechanical and adhesion properties[J]. http://dx.doi.org/10.1039/c3sm50879j,2013.
APA Dana, Sara Faraji,Duc-Viet Nguyen,Kochhar, Jaspreet Singh,Liu, Xiang-Yang,Kang, Lifeng,&刘向阳.(2013).UV-curable pressure sensitive adhesive films: effects of biocompatible plasticizers on mechanical and adhesion properties.http://dx.doi.org/10.1039/c3sm50879j.
MLA Dana, Sara Faraji,et al."UV-curable pressure sensitive adhesive films: effects of biocompatible plasticizers on mechanical and adhesion properties".http://dx.doi.org/10.1039/c3sm50879j (2013).
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