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	Numerical modeling and simulation of temperature distribution uncertainty subject to ferromagnetic thermoseeds hyperthermia
	Zi-Han Zhuo ; Jie Wang ; Wei-Ming Zhai ; Heng Wang ; Jin-Tian Tang ; Zi-Han Zhuo ; Jie Wang ; Wei-Ming Zhai ; Heng Wang ; Jin-Tian Tang
	2016-03-30 ; 2016-03-30
关键词	Magnetic induction hyperthermia Temperature distribution Ferromagnetic thermoseeds Treatment planning Uncertainty R454.1
其他题名	Numerical modeling and simulation of temperature distribution uncertainty subject to ferromagnetic thermoseeds hyperthermia
中文摘要	In the process of ferromagnetic thermoseeds mediated magnetic induction hyperthermia,the temperature distribution in the tumor region is a key factor to determine the therapy effect.During the preoperative treatment planning,discrepancies of the treatment parameters may lead to the temperature distribution uncertainty within the target area.Inaccurate prediction of temperature distribution may induce the treatment failure;therefore,it would be significant to investigate the uncertainty of tissue temperature prediction caused by the disturbance of calculation parameters.In this paper,3D temperature field and necrosis zone of tissues in ferromagnetic thermoseeds hyperthermia are simulated by the finite volume algorithm,and effects of parameter uncertainties on the temperature distribution are revealed.Results show that selecting appropriate magnetic field parameters for treatment is a priority to guarantee therapeutic effect.Thermoseed properties and blood perfusion rate are the obvious disturbing terms for temperature distribution,while the metabolic heat of bio-tissues can often be ignored within limits.Our investigation is of importance for guiding reasonable and optimal preoperative treatment planning.; In the process of ferromagnetic thermoseeds mediated magnetic induction hyperthermia, the temperature distribution in the tumor region is a key factor to determine the therapy effect. During the preoperative treatment planning, discrepancies of the treatment parameters may lead to the temperature distribution uncertainty within the target area. Inaccurate prediction of temperature distribution may induce the treatment failure; therefore, it would be significant to investigate the uncertainty of tissue temperature prediction caused by the disturbance of calculation parameters. In this paper, 3D temperature field and necrosis zone of tissues in ferromagnetic thermoseeds hyperthermia are simulated by the finite volume algorithm,and effects of parameter uncertainties on the temperature distribution are revealed. Results show that selecting appropriate magnetic field parameters for treatment is a priority to guarantee therapeutic effect. Thermoseed properties and blood perfusion rate are the obvious disturbing terms for temperature distribution, while the metabolic heat of bio-tissues can often be ignored within limits. Our investigation is of importance for guiding reasonable and optimal preoperative treatment planning.
语种	英语 ; 英语
内容类型	期刊论文
源URL	[http://ir.lib.tsinghua.edu.cn/ir/item.do?handle=123456789/143272]
专题	清华大学
推荐引用方式 GB/T 7714	Zi-Han Zhuo,Jie Wang,Wei-Ming Zhai,et al. Numerical modeling and simulation of temperature distribution uncertainty subject to ferromagnetic thermoseeds hyperthermia[J],2016, 2016.
APA	Zi-Han Zhuo.,Jie Wang.,Wei-Ming Zhai.,Heng Wang.,Jin-Tian Tang.,...&Jin-Tian Tang.(2016).Numerical modeling and simulation of temperature distribution uncertainty subject to ferromagnetic thermoseeds hyperthermia..
MLA	Zi-Han Zhuo,et al."Numerical modeling and simulation of temperature distribution uncertainty subject to ferromagnetic thermoseeds hyperthermia".(2016).

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