Controlled photopolymerization of hydrogel microstructures inside microchannels for bioassays | |
Liu, Jiangjiang ; Gao, Dan ; Li, Hai-Fang ; Lin, Jin-Ming | |
2010-10-12 ; 2010-10-12 | |
关键词 | MICROFLUIDIC SYSTEMS FLOW LITHOGRAPHY FABRICATION PHOTOLITHOGRAPHY MICROREACTORS MICROARRAYS MICROSCOPE CHIP Biochemical Research Methods Chemistry, Multidisciplinary Nanoscience & Nanotechnology |
中文摘要 | This paper describes a photolithography approach to generate hydrogel microstructures inside microchannels on the basis of controlled photopolymerization of poly(ethylene glycol) diacrylate precursor by using a fluorescence microscope. The controlled photopolymerization offers: (1) morphology control on hydrogel microstructures with different illumination conditions; (2) position control on hydrogel microstructures to make it possible for the generation of arrayed hydrogel microstructures and encapsulation of single cells; (3) a convenient approach for immobilization of a variety of materials onto the solid substrates for bioassays. For demonstration, we performed a microfluidic assay for DNA oligomer detection on the arrayed hydrogel microstructures. |
语种 | 英语 ; 英语 |
出版者 | ROYAL SOC CHEMISTRY ; CAMBRIDGE ; THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND |
内容类型 | 期刊论文 |
源URL | [http://hdl.handle.net/123456789/80844] |
专题 | 清华大学 |
推荐引用方式 GB/T 7714 | Liu, Jiangjiang,Gao, Dan,Li, Hai-Fang,et al. Controlled photopolymerization of hydrogel microstructures inside microchannels for bioassays[J],2010, 2010. |
APA | Liu, Jiangjiang,Gao, Dan,Li, Hai-Fang,&Lin, Jin-Ming.(2010).Controlled photopolymerization of hydrogel microstructures inside microchannels for bioassays.. |
MLA | Liu, Jiangjiang,et al."Controlled photopolymerization of hydrogel microstructures inside microchannels for bioassays".(2010). |
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