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	107例矫正型大动脉转位手术治疗中期结果分析
	花中东 ; 胡盛寿 ; 潘湘斌 ; 沈向东 ; 李守军 ; 阎军 ; 刘迎龙 ; 吴清玉 ; 王旭 ; HUA Zhong-dong ; HU Sheng-shou ; PAN Xiang-bin ; SHEN Xiang-dong ; LI Shou-jun ; YAN Jun ; LIU Ying-long ; WU Qing-yu ; WANG Xu
	2010-06-09 ; 2010-06-09
关键词	矫正型大动脉转位 心脏外科 Corrected congenital transposition of great arteries Cardiac surgery R654.2
其他题名	Operative and Mid-Term Results of 107 Corrected Congenital Transposion of Great Arteries
中文摘要	目的:报告并分析我院107例手术治疗矫正型大动脉转位(CCTGA)合并心内畸形患者的中期随访结果。方法:1996-01至2005-12,在我院手术治疗CCTGA合并心内畸形患者107例,其中男72例,女35例;年龄1.5～50岁,平均(11.5±8.4)岁;平均体重(31.6±4.7)kg。81例左位心,23例右位心,3例中位心。手术方式包括传统双心室功能矫治75例;单心室分期矫治14例;双心室解剖矫治18例。结果:术后早期死亡5例,死亡率为4.7%。传统双心室功能矫治死亡率为4.0%;单心室分期矫治死亡率为0%;心房动脉双调转手术死亡率为0%;心房心室双调转手术死亡率40.0%。手术死亡危险因素为复杂心内畸形合并肺动脉瓣狭窄(P<0.01),与其他危险因素相比差异有统计学意义。共随访99例,随访率为92.5%。随访期间死亡12例,死亡率为12.1%;其中10例(83.3%)属于传统双心室功能矫治患者,2例(16.7%)属于单心室矫治患者。双心室解剖矫治患者没有死亡。随访期死亡危险因素为传统功能矫治手术方式(P<0.05),心房心室双调转手术(P<0.05),与其他手术方式相比差异有统计学意义。结论:CCTGA传统手术方法的中期结果是令人失望的。对于适合单心室矫治的CCTGA病例,手术可以取得较好的中期结果。心房动脉双调转手术中期的死亡率低,并发症少,其手术结果是值得肯定的。; Objective:To retrospectively analyze the results and mid-term outcomes of 107 patients with corrected congenital transposition of great arteries(CCTGA)who underwent surgical treatment.Methods:A total of 107 CCTGA patients with surgical treatment from January 1996 to October 2005 in our hospital were studied.There were 72 male and 35 female,with the mean age of 11.5�4years and mean body weight of 31.6�7kg.Among the cohort,81 were levocardia,23 dextrocardia,and 3 medocardia.Initial surgical procedure included single ventricle repair in 14 cases,conventional biventricular repair in 75 and biventricular anatomical repair in 18 cases.99(93%)patients were followed up with the mean time of 47.8 months.Results:The early operative mortality rate was 4.76% in different procedures.The death rate with single ventricle repair was 0%,conventional biventricular repair 4%,atrial-arterial double switch 0%,atrial-ventricular double switch 40%.The risk factors for operative mortality were lesions with double outlet left ventricle combined with pulmonary stenosis(P<0.01)and Rastelli procedure(P<0.05).12 patients(12.6%)died during the follow up period,among them,10(83.3%)were in conventional repair group,2(16.7%)in single ventricle repair group,and no death in double switch group.The risk of death during the follow up period of time were conventional biventricular repair,Rastelli procedure and tricuspid regurgitation.Conclusion:Conventional biventricular repair had a disappointing outcome in both operation and in long-term of follow up time.Patients suitable for single ventricular repair had fair short-and mid-term outcomes.Atrial-arterial double switch procedure had good operation and long-term results.
语种	中文 ; 中文
内容类型	期刊论文
源URL	[http://hdl.handle.net/123456789/59134]
专题	清华大学
推荐引用方式 GB/T 7714	花中东,胡盛寿,潘湘斌,等. 107例矫正型大动脉转位手术治疗中期结果分析[J],2010, 2010.
APA	花中东.,胡盛寿.,潘湘斌.,沈向东.,李守军.,...&WANG Xu.(2010).107例矫正型大动脉转位手术治疗中期结果分析..
MLA	花中东,et al."107例矫正型大动脉转位手术治疗中期结果分析".(2010).

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