QQ客服 官方微博 反馈留言

	Potential ability of hematoporphyrin to enhance an optical coherence tomographic image of gastric cancer in vivo in mice
	Xiong, Honglian ; Zeng, Changchun ; Guo, Zhouyi ; Zhong, Huiqing ; Wang, Ruikang ; Liu, Songhao ; He, Yonghong
	2010-05-11 ; 2010-05-11
关键词	ATHEROSCLEROTIC PLAQUE CONSTITUENTS ATTENUATION COEFFICIENTS CELL CARCINOMA FEASIBILITY SCATTERING ESOPHAGUS TISSUE BIOPSY TRACT Engineering, Biomedical Radiology, Nuclear Medicine & Medical Imaging
中文摘要	An ideal diagnostic system for the tumor tissues should be able to detect and define the location of tumor tissues and the early development of malignant diseases. There is great need for enhancement of imaging ability to tumor tissues. Optical coherence tomography (OCT) is used in detection and location of varied tumor tissues. In order to improve the sensitivity and specificity of an OCT image, hematoporphyrin as a new type of contrast agent was used in this study. The orthotopic graft model of gastric cancer in nude mice was used. The image formations of the tumor tissues without and with injection of hematoporphyrin in vivo were obtained by an OCT system at a 1310 nm central wavelength. The experimental results showed that the tumor tissues accumulated with hematoporphyrin have an ability of light absorption which results in the increase of signal attenuation in the gastric cancer tissues, and that the boundary between the tumor tissues and surrounding normal tissues was perfectly defined owing to the accumulation of hematoporphyrin. From the experimental results, it is found that hematoporphyrin, a photosensitizing agent, could be used as a contrast agent for OCT imaging of tumor tissues, which offer an effective OCT image method for clinical detection and localization of tumor tissues in vivo.
语种	英语 ; 英语
出版者	IOP PUBLISHING LTD ; BRISTOL ; DIRAC HOUSE, TEMPLE BACK, BRISTOL BS1 6BE, ENGLAND
内容类型	期刊论文
源URL	[http://hdl.handle.net/123456789/26442]
专题	清华大学
推荐引用方式 GB/T 7714	Xiong, Honglian,Zeng, Changchun,Guo, Zhouyi,et al. Potential ability of hematoporphyrin to enhance an optical coherence tomographic image of gastric cancer in vivo in mice[J],2010, 2010.
APA	Xiong, Honglian.,Zeng, Changchun.,Guo, Zhouyi.,Zhong, Huiqing.,Wang, Ruikang.,...&He, Yonghong.(2010).Potential ability of hematoporphyrin to enhance an optical coherence tomographic image of gastric cancer in vivo in mice..
MLA	Xiong, Honglian,et al."Potential ability of hematoporphyrin to enhance an optical coherence tomographic image of gastric cancer in vivo in mice".(2010).

个性服务

查看访问统计

相关权益政策

暂无数据

收藏/分享

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。